CAJ | 학술논문

目的：评价介入封堵术治疗伴有卵圆孔未闭偏头痛患者的效果。方法选取2013年1月~2014年1月在本院神经内科就诊的偏头痛患者，同时接受经颅多普勒和经胸心脏超声(TTE)发泡实验阳性，后经食道超声确诊为卵圆孔未闭，并在本院心内一科接受卵圆孔未闭封堵治疗的患者30例。术前及术后行HIT-6评分对头痛症状是否缓解进行评估，术后行TTE发泡实验复查封堵效果。结果30例患者手术均成功，在院及随访期间无手术并发症出现。术前的HIT-6评分为(70±5)分，术后的HIT-6评分为(49±3)分，差异有统计学意义(P<0.05)。术后1个月复查TTE均显示封堵器位置良好，TTE发泡实验27例分流消失，3例仍有残余分流。结论卵圆孔未闭封堵术可以明显缓解伴有卵圆孔未闭的偏头痛患者的头痛症状。
목적：평개개입봉도술치료반유란원공미폐편두통환자적효과。방법선취2013년1월~2014년1월재본원신경내과취진적편두통환자，동시접수경로다보륵화경흉심장초성(TTE)발포실험양성，후경식도초성학진위란원공미폐，병재본원심내일과접수란원공미폐봉도치료적환자30례。술전급술후행HIT-6평분대두통증상시부완해진행평고，술후행TTE발포실험복사봉도효과。결과30례환자수술균성공，재원급수방기간무수술병발증출현。술전적HIT-6평분위(70±5)분，술후적HIT-6평분위(49±3)분，차이유통계학의의(P<0.05)。술후1개월복사TTE균현시봉도기위치량호，TTE발포실험27례분류소실，3례잉유잔여분류。결론란원공미폐봉도술가이명현완해반유란원공미폐적편두통환자적두통증상。
Objective To evaluate the effect of interventional closure in the treatment of patients with migraine com-bined with patent foramen ovale. Methods 30 patients with migraine who were tested positive in contrast transcranial Doppler and echocardiographic contrast and defined patent foramen ovale by transoesopheageal echocardiography(TEE) at the department of neurology in our hospital from January 2013 to January 2014.Procedures of transcatheter closure of patent foramen ovale were performed for all patients at department of cardiology in our hospital.After transcatheterclo-sure the patients were re-examined by TCDs and TTE and interviewed with headache impact test-6 (HIT-6)question-naire to elevate improvement of migraine.The data were analyzed. Results Percutaneous closure was successful in all patients.In the court and during the follow-up period had no complication appeared.Preoperative HIT-6 score was (70±5)points,postoperative HIT-6 score was(49±3) points,with statistical difference(P<0.05).After operation 1 month,re-ex-amined by TTE for evaluate the site of occluder and re-examined TTE contrast,the shunt was disappear in 27 patients, 3 cases were still residual shunt. Conclusion Interventional closure can obviously relieve headache of patients with mi-graine combined with patent foramen ovale.