CAJ | 학술논문

目的：分析检测患Graves病孕妇血清中促甲状腺激素受体抗体（TRAb）的临床价值。方法选择我院诊治的35例患Graves病孕妇作为实验组，另选35例健康体检孕妇作为对照组，ELISA法检测两组孕妇血清中TRAb浓度，化学发光免疫法检测游离三碘甲腺原氨酸（FT3）、游离甲状腺素（FT4）的含量水平。结果实验组孕妇血清中TRAb、FT3、FT4含量明显高于对照组，服用药物治疗3个月含量仍然高于正常值，6个月后趋于正常。结论检测孕妇Graves病患者血清中TRAb含量不仅对于Graves病的诊断、疗效观察有重要意义，还可指导临床治疗用药量及治疗时机。
목적：분석검측환Graves병잉부혈청중촉갑상선격소수체항체（TRAb）적림상개치。방법선택아원진치적35례환Graves병잉부작위실험조，령선35례건강체검잉부작위대조조，ELISA법검측량조잉부혈청중TRAb농도，화학발광면역법검측유리삼전갑선원안산（FT3）、유리갑상선소（FT4）적함량수평。결과실험조잉부혈청중TRAb、FT3、FT4함량명현고우대조조，복용약물치료3개월함량잉연고우정상치，6개월후추우정상。결론검측잉부Graves병환자혈청중TRAb함량불부대우Graves병적진단、료효관찰유중요의의，환가지도림상치료용약량급치료시궤。
Objective Analysis testing of pregnant women suffering from Graves' disease serum thyrotropin receptor antibody(TRAb)clinical value. Methods 35 patients in our hospital for treatment of pregnant women suffering from Graves' disease as the experimental group, choose another 35 cases as a control group of healthy pregnant women, ELISA assay two maternal serum TRAb concentration, chemiluminescence immunoassay of free iodine Thyroid three original ammonia acid(FT3), free thyroxine(FT4)levels levels.Results The maternal serum TRAb, FT3, FT4 levels signiifcantly higher, taking medication for 3 months is still higher than normal levels, after 6 months tended to be normal.Conclusion The maternal Graves TRAb levels in serum of patients with Graves' disease not only for diagnosis, efifcacy is important, but also to guide clinical treatment dosage and timing of treatment.