CAJ | 학술논문

目的：探讨儿童支原体肺炎急性期血清心肌酶谱变化及其临床意义。方法选取2012年8月~2013年8月本院诊治的180例支原体肺炎急性期患儿为观察组，以同期40例健康体检儿童作为对照组，分析心肌酶检测结果及其临床意义；并将观察组中122例心肌酶谱异常的患儿根椐临床症状分为轻症组、重症组，分析心肌酶水平变化情况。结果观察组的CK-MB、LDH、CK、α-HBDH及AST水平均高于对照组，差异有统计学意义(P<0.05)。重症组的CK-MB、LDH、CK、α-HBDH及AST水平均高于轻症组，差异有统计学意义(P<0.05)。心肌酶谱高患儿恢复期组与对照组的心肌酶谱比较，差异无统计学意义(P>0.05)。结论支原体肺炎急性期患儿存在不同程度的心肌损伤，血清心肌酶CK-MB能特异性反映心肌损伤，并指导进一步治疗。
목적：탐토인동지원체폐염급성기혈청심기매보변화급기림상의의。방법선취2012년8월~2013년8월본원진치적180례지원체폐염급성기환인위관찰조，이동기40례건강체검인동작위대조조，분석심기매검측결과급기림상의의；병장관찰조중122례심기매보이상적환인근거림상증상분위경증조、중증조，분석심기매수평변화정황。결과관찰조적CK-MB、LDH、CK、α-HBDH급AST수평균고우대조조，차이유통계학의의(P<0.05)。중증조적CK-MB、LDH、CK、α-HBDH급AST수평균고우경증조，차이유통계학의의(P<0.05)。심기매보고환인회복기조여대조조적심기매보비교，차이무통계학의의(P>0.05)。결론지원체폐염급성기환인존재불동정도적심기손상，혈청심기매CK-MB능특이성반영심기손상，병지도진일보치료。
Objective To study the change and clinical significance of serum myocardial enzyme in children with My-coplasma pneumonia during the acute period. Methods The 180 children of patients with Mycoplasma pneumonia dur-ing the acute period and 40 health examination children in our hospital during the period from August 2012 to August 2013 were selected as observation group and control group respectively,and clinical significance of myocardial enzyme test results were analysed.122 cases of myocardial enzyme children in observation group were divided into mild group and severe group according to clinical symptom,the change of myocardial enzyme level was analysed. Results CK-MB, LDH,CK,α-HBDH,AST in observation group was higher than that in control group respectively,with statistical differ-ence(P<0.05).CK-MB,LDH,CK,α-HBDH,AST in severe group was higher than that in mild group respectively,with sta-tistical difference (P<0.05).Myocardial enzymes in recovery group of children with high myocardial enzyme and control group was compared respectively,with no statistical difference (P>0.05). Conclusion Mycoplasma pneumoniae in chil-dren with acute myocardial damage of different level,serum CK-MB could specifically reflect myocardial damage and to guide further treatment.