中国当代医药
中國噹代醫藥
중국당대의약
PERSON
2014年
17期
18-20
,共3页
魔芋精粉%酒精性肝损伤%保护作用
魔芋精粉%酒精性肝損傷%保護作用
마우정분%주정성간손상%보호작용
Konjac powder%Alcoholic liver injury%Protective effect
目的：研究魔Ⅲ精粉对大鼠酒精性肝损伤的保护作用。方法将40只SD大鼠随机分为正常对照组(10只)、模型组(14只)、魔Ⅲ精粉组(16只)，用白酒灌胃的方式建立大鼠酒精性肝损伤模型，12周后，测定大鼠血液中丙氨酸氨基转移酶(ALT)、天冬氨酸氨基转移酶(AST)及肝组织水平。结果魔Ⅲ精粉组中ALT、AST的含量均低于模型组(P<0.05)，大鼠肝组织中丙二醛含量低于模型组(P<0.05)，超氧化物歧化酶活性高于模型组(P<0.05)。结论魔Ⅲ精粉对酒精性肝损伤有一定的保护作用。
目的：研究魔Ⅲ精粉對大鼠酒精性肝損傷的保護作用。方法將40隻SD大鼠隨機分為正常對照組(10隻)、模型組(14隻)、魔Ⅲ精粉組(16隻)，用白酒灌胃的方式建立大鼠酒精性肝損傷模型，12週後，測定大鼠血液中丙氨痠氨基轉移酶(ALT)、天鼕氨痠氨基轉移酶(AST)及肝組織水平。結果魔Ⅲ精粉組中ALT、AST的含量均低于模型組(P<0.05)，大鼠肝組織中丙二醛含量低于模型組(P<0.05)，超氧化物歧化酶活性高于模型組(P<0.05)。結論魔Ⅲ精粉對酒精性肝損傷有一定的保護作用。
목적：연구마Ⅲ정분대대서주정성간손상적보호작용。방법장40지SD대서수궤분위정상대조조(10지)、모형조(14지)、마Ⅲ정분조(16지)，용백주관위적방식건립대서주정성간손상모형，12주후，측정대서혈액중병안산안기전이매(ALT)、천동안산안기전이매(AST)급간조직수평。결과마Ⅲ정분조중ALT、AST적함량균저우모형조(P<0.05)，대서간조직중병이철함량저우모형조(P<0.05)，초양화물기화매활성고우모형조(P<0.05)。결론마Ⅲ정분대주정성간손상유일정적보호작용。
Objective To study the protective effect of konjac powder in rats with alcoholic liver injury. Methods Forty SD rats were randomly divided into 3 groups:normal group (n=10),model group (n=14),and konjac powder group (n=16). The model of rat with alcoholic liver injury was created by liquor gavage.After 12 weeks,the levels of alanine transami-nase (ALT),aspartate aminotransferase (AST),and hepatic tissues in rat’s blood were measured. Results In comparison with the model group,the content of ALT and AST in the konjac powder group were both lower (P<0.05).The content of methane dicarboxylic aldehyde from hepatic tissue in rat in the konjac powder group was lower than that in the model group (P<0.05).The activity of superoxide dismutase from hepatic tissue in konjac powder group was higher than that in the model group (P<0.05). Conclusion Konjac powder has a certain protective effect on alcoholic liver injury.
