CAJ | 학술논문

目的：探讨女性患者围术期肺血栓栓塞症（PE）发生率与体质量指数（BMI）的相关性。方法对2001～2012年该院140例女性手术患者并发PE临床资料进行回顾性研究，其中57例特发性 PE，83例非特发性 PE（与手术创伤以及恶性肿瘤有关）。BMI分为6个等级：＜22．5、22．5～＜25．0、25．0～＜27．5、27．5～＜30．0、30．0～＜35．0、≥35．0 kg/m2。多变量 Cox比例危险度模型变量有年龄、吸烟、生产次数、绝经期，药物摄入包括非甾类抗炎药、华法林使用情况，合并症包括原发性高血压、冠心病。结果 BMI与特发性PE（RR＝1．08，95％CI：1．06～1．10，P＜0．01）和非特发性 PE（RR＝1．08，95％CI：1．07～1．10，P＜0．01），均有较强的直线相关性。当BMI ≥35 kg/m2，危险度增加6倍。结论女性 BMI增加与 PE的发生有显著的线性相关， BMI可作为评估围术期PE的危险因素。
목적：탐토녀성환자위술기폐혈전전새증（PE）발생솔여체질량지수（BMI）적상관성。방법대2001～2012년해원140례녀성수술환자병발PE림상자료진행회고성연구，기중57례특발성 PE，83례비특발성 PE（여수술창상이급악성종류유관）。BMI분위6개등급：＜22．5、22．5～＜25．0、25．0～＜27．5、27．5～＜30．0、30．0～＜35．0、≥35．0 kg/m2。다변량 Cox비례위험도모형변량유년령、흡연、생산차수、절경기，약물섭입포괄비치류항염약、화법림사용정황，합병증포괄원발성고혈압、관심병。결과 BMI여특발성PE（RR＝1．08，95％CI：1．06～1．10，P＜0．01）화비특발성 PE（RR＝1．08，95％CI：1．07～1．10，P＜0．01），균유교강적직선상관성。당BMI ≥35 kg/m2，위험도증가6배。결론녀성 BMI증가여 PE적발생유현저적선성상관， BMI가작위평고위술기PE적위험인소。
Objective To study the correlation between the occurrence rate of perioperative pulmonary thromboembolism(PE) and the body mass index(BMI)in female patients.Methods 140 operative female cases complicating PE in this hospital from 2001 to 2012 were retrospectively studied.57 cases were idiopathic PE and 83 cases were non-idiopathic PE(related with surgery,trau-ma,and malignancy).BMI was divided into 6 levels:<22.5,22.5-<25.0,25.0-<27.5,27.5-<30.0,30.0-<35.0,≥ 35.0 kg/m2 .The multivariate Cox proportional hazards model variable included age,smoking,parturition times,menopause,drug intake of non-steroidal anti-inflammatory drugs,warfarin,coexisting diseases including hypertension,coronary heart disease.Results BMI had stronger linear correlation with the occurrence rate of PE.The relative risk between BMI and idiopathic PE was(RR=1.08, 95%CI:1.06-1.10,P<0.01).The relative risk between BMI and non-idiopathic PE was(RR=1.08,95%CI:1.07-1.10,P<0.01).When BMI ≥ 35 kg/m2 ,the risk was increased by 6 times.Conclusion The BMI increase in female patients has significant linear correlation with the occurrence of PE.BMI could be considered as a risk factor for assessing perioperative PE.