肿瘤影像学
腫瘤影像學
종류영상학
Oncoradiology
2014年
3期
196-199
,共4页
18F-脱氧葡萄糖%双探头符合线路断层显像%99mTc-亚甲基二膦酸盐骨显像%骨转移
18F-脫氧葡萄糖%雙探頭符閤線路斷層顯像%99mTc-亞甲基二膦痠鹽骨顯像%骨轉移
18F-탈양포도당%쌍탐두부합선로단층현상%99mTc-아갑기이련산염골현상%골전이
18F-fluorodeoxyglucose%Dual-head tomography with coincidence%99mTc-methylenediphosphonate bone scintigraphy%Bone metastasis
目的：比较18F-脱氧葡萄糖（18F-FDG）符合探测显像及99mTc-亚甲基二膦酸盐（99mTc-MDP）骨显像在肿瘤骨转移诊断及疗效评价中的价值。方法收集本院行18F-FDG符合探测显像及99mTc-MDP骨显像的骨转移患者42例，平均年龄（53.62±12.48）岁。其中未进行任何治疗患者18例，另11例治疗后多次（2~5次）行18F-FDG符合探测显像及99mTc-MDP全身骨显像。两种检查在1周内完成。比较两种方法在肿瘤骨转移诊断及疗效评价中的价值。结果18F-FDG符合探测显像有36例明确诊断，99mTc-MDP骨显像有32例明确诊断，两种方法的诊断准确率差异无统计学意义（χ2=1.25，P=0.320）。18例未行治疗患者中，18F-FDG符合探测显像均明确诊断，99mTc-MDP骨显像有12例明确诊断，两种方法的诊断准确率差异有统计学意义（χ2=4.17，P＜0.05）。治疗后疗效评价，符合探测显像复查结果与临床疗效评估结果有较强的正相关性（r=0.834，P＜0.02）。结论18F-FDG符合探测显像在初诊骨转移患者诊断及患者疗效评价中较99mTc-MDP骨显像有优势。
目的：比較18F-脫氧葡萄糖（18F-FDG）符閤探測顯像及99mTc-亞甲基二膦痠鹽（99mTc-MDP）骨顯像在腫瘤骨轉移診斷及療效評價中的價值。方法收集本院行18F-FDG符閤探測顯像及99mTc-MDP骨顯像的骨轉移患者42例，平均年齡（53.62±12.48）歲。其中未進行任何治療患者18例，另11例治療後多次（2~5次）行18F-FDG符閤探測顯像及99mTc-MDP全身骨顯像。兩種檢查在1週內完成。比較兩種方法在腫瘤骨轉移診斷及療效評價中的價值。結果18F-FDG符閤探測顯像有36例明確診斷，99mTc-MDP骨顯像有32例明確診斷，兩種方法的診斷準確率差異無統計學意義（χ2=1.25，P=0.320）。18例未行治療患者中，18F-FDG符閤探測顯像均明確診斷，99mTc-MDP骨顯像有12例明確診斷，兩種方法的診斷準確率差異有統計學意義（χ2=4.17，P＜0.05）。治療後療效評價，符閤探測顯像複查結果與臨床療效評估結果有較彊的正相關性（r=0.834，P＜0.02）。結論18F-FDG符閤探測顯像在初診骨轉移患者診斷及患者療效評價中較99mTc-MDP骨顯像有優勢。
목적：비교18F-탈양포도당（18F-FDG）부합탐측현상급99mTc-아갑기이련산염（99mTc-MDP）골현상재종류골전이진단급료효평개중적개치。방법수집본원행18F-FDG부합탐측현상급99mTc-MDP골현상적골전이환자42례，평균년령（53.62±12.48）세。기중미진행임하치료환자18례，령11례치료후다차（2~5차）행18F-FDG부합탐측현상급99mTc-MDP전신골현상。량충검사재1주내완성。비교량충방법재종류골전이진단급료효평개중적개치。결과18F-FDG부합탐측현상유36례명학진단，99mTc-MDP골현상유32례명학진단，량충방법적진단준학솔차이무통계학의의（χ2=1.25，P=0.320）。18례미행치료환자중，18F-FDG부합탐측현상균명학진단，99mTc-MDP골현상유12례명학진단，량충방법적진단준학솔차이유통계학의의（χ2=4.17，P＜0.05）。치료후료효평개，부합탐측현상복사결과여림상료효평고결과유교강적정상관성（r=0.834，P＜0.02）。결론18F-FDG부합탐측현상재초진골전이환자진단급환자료효평개중교99mTc-MDP골현상유우세。
Objective To compare the value of 18F-fluorodeoxyglucose (18F-FDG) dual-head tomography with coincidence (DHTC) and 99mTc-methylenediphosphonate (99mTc-MDP) bone scintigraphy (BS) in diagnosis and therapeutic evaluation of bone metastases. Methods A total of 42 cases with cancer bone metastases, averagely aged (53.62±12.48) years old, were enrolled in this study. 18 cases did not receive any treatment, and 11 patients received inspection 2-5 times for assessment of therapeutic effects. 18F-FDG DHTC and 99mTc-MDP BS were performed within one week in all patients. The sensitivity, specificity and accuracy of 18F-FDG DHTC and 99mTc-MDP BS were compared. Results Of the 42 patients with bone metastases, 36 cases were correctly detected by 18F-FDG DHTC, and 32 were correctly detected by 99mTc-MDP BS. The difference of the sensitivity was not significant (χ2=1.25,P=0.320). Among 18 patients who did not receive any treatment, all got correct diagnosis by 18F-FDG DHTC, and 12 were positive on 99mTc-MDP BS. The difference of the diagnostic accuracy was significant (χ2=4.17,P<0.05). The result of 18F-FDG DHTC was strongly correlated with the clinical therapeutic evaluation(r=0.834,P<0.02). Conclusion 18F-FDG DHTC offers an advantage in diagnosis and therapeutic evaluation of bone metastases over 99mTc-MDP BS.
