CAJ | 학술논문

目的：明确癌症患者死亡前6个月乳酸脱氢酶（lactate dehydrogenase，LDH）水平的变化趋势，评估LDH水平对患者预后和生存时间是否具有预测性。方法回顾性分析216例癌症死亡患者的一般情况和疾病特征与LDH水平之间的相关性。结果越临近死亡，癌症患者的LDH水平越高，患者的性别、年龄、肿瘤类型和分期与LDH水平之间的相关性无统计学意义（P＞0.05）。结论 LDH水平的升高预示了癌症患者不良预后和有限的生存时间。
목적：명학암증환자사망전6개월유산탈경매（lactate dehydrogenase，LDH）수평적변화추세，평고LDH수평대환자예후화생존시간시부구유예측성。방법회고성분석216례암증사망환자적일반정황화질병특정여LDH수평지간적상관성。결과월림근사망，암증환자적LDH수평월고，환자적성별、년령、종류류형화분기여LDH수평지간적상관성무통계학의의（P＞0.05）。결론 LDH수평적승고예시료암증환자불량예후화유한적생존시간。
Objective To find out the change trend of LDH values in cancer patients' last 6 months of life, and to evaluate whether LDH level was a predictor for on patients' prognosis and survival time. Method A retrospec-tive analysis including 216 patients was conducted to assess the correlation between their demographic characteris-tics, disease characteristics and the level of LDH. Results Patients that were closer to death had higher LDH level. In addition, the correlation between patients' gender, age, tumor type, tumor stage and LDH levels was insignificant (P > 0.05). Conclusion The increase of LDH level indicates poorer prognosis and limited survival time in cancer patients.