海峡药学
海峽藥學
해협약학
STRAIT PHARMACEUTICAL JOURNAL
2014年
9期
80-84
,共5页
促黄体激素释放激素%抗肿瘤%缀合物
促黃體激素釋放激素%抗腫瘤%綴閤物
촉황체격소석방격소%항종류%철합물
Luteinizing hormone-releasing hormone%Antitumor%Conjugate
前列腺癌是男性癌症患者中最常见的疾病之一,对晚期前列腺癌症的治疗方法常见的是雄激素阻断疗法,而促黄体激素释放激素的发现为雄激素阻断疗法开辟了新的道路。本文综述了各类促黄体激素释放激素类似物在抗肿瘤方面的应用,并讨论其作用机制。
前列腺癌是男性癌癥患者中最常見的疾病之一,對晚期前列腺癌癥的治療方法常見的是雄激素阻斷療法,而促黃體激素釋放激素的髮現為雄激素阻斷療法開闢瞭新的道路。本文綜述瞭各類促黃體激素釋放激素類似物在抗腫瘤方麵的應用,併討論其作用機製。
전렬선암시남성암증환자중최상견적질병지일,대만기전렬선암증적치료방법상견적시웅격소조단요법,이촉황체격소석방격소적발현위웅격소조단요법개벽료신적도로。본문종술료각류촉황체격소석방격소유사물재항종류방면적응용,병토론기작용궤제。
Prostate cancer is one of the most common cancer among men.Commonly ,the patients with advanced-prostate cancer are treated with androgen deprivation therapy.The discovery of luteinizing hormone-releasing hormone opens up a new window of androgen deprivation therapy.In this paper ,we reviewed a series of luteinizing hormone-re-leasing hormone analogs with antitumor activity ,and the mechanism of action was also discussed.