CAJ | 학술논문

目的：探讨白鹤灵芝对肾上腺素所致高血糖模型的影响，并初步探讨其实用性。方法采用腹腔注射肾上腺素引起的高血糖小鼠动物模型及正常小鼠，分别以白鹤灵芝水提物不同剂量组进行灌胃，给药结束后测定血糖水平。结果腹腔注射肾上腺素30min后，阳性组和白鹤灵芝中高剂量组（15.2、7.6g· kg1）能明显对抗肾上腺素引起的升血糖作用（P＜0.05），白鹤灵芝低剂量组（3.8g· kg 1）对肾上腺素引起的高血糖作用不明显（ P＞0.05）。结论白鹤灵芝具有明显的对抗对肾上腺素所致高血糖的作用。
목적：탐토백학령지대신상선소소치고혈당모형적영향，병초보탐토기실용성。방법채용복강주사신상선소인기적고혈당소서동물모형급정상소서，분별이백학령지수제물불동제량조진행관위，급약결속후측정혈당수평。결과복강주사신상선소30min후，양성조화백학령지중고제량조（15.2、7.6g· kg1）능명현대항신상선소인기적승혈당작용（P＜0.05），백학령지저제량조（3.8g· kg 1）대신상선소인기적고혈당작용불명현（ P＞0.05）。결론백학령지구유명현적대항대신상선소소치고혈당적작용。
OBJECTIVE To investigate effect of extracts from Rhinacanthus nasutus on hyperglycemia caused by adrenaline and discuss its practicability.METHODS The mouse models of hyperglycemia caused by injecting epinephrine and the normal mice were adopted.After different doses of intragastric administration with extracts from Rhinacanthus nasutus on the two groups ,the blood glucose levels of each group was determined.RESULTS After intraperitoneal injection of epinephrine of 30 min, posi-tive control group and Rhinacanthus nasutus dosage ( 15.2 , 7.6 g· kg -1 ) had better therapeutical effect on diabetes mice induced by epinephrine ( P<0.05 ) ,while Rhinacan-thus nasutus group with 3.8 g· kg -1 dosage had no the rapeutical effect ( P>0.05 ).CONCLUSION The extracts from Rhinacanthus nasutus has good hypoglycemic effect on many kinds of diabetic animals .