中国斜视与小儿眼科杂志
中國斜視與小兒眼科雜誌
중국사시여소인안과잡지
CHINESE JOURNAL OF STRABISMUS & PEDIATRIC OPHTHALMOLOGY
2014年
3期
41-44,19
,共5页
视觉系统的神经网络是由许多神经元通过突触联系而形成的。遗传因素为年幼个体的突触联系奠定了良好的基础,而网络中的突触联系又是在内、外界环境因素的影响下,不断地发育和完善,因而突触联系便有了可塑性和敏感期,而且与一些疾病(如:弱视)的发病机理密切相关。随着电生理(尤其是膜片钳方法)和分子生物学技术的迅猛发展,近年来对这些课题进行了更深入的研究,本文综述国内外在这方面的一些新观念和所取得的新成果。
視覺繫統的神經網絡是由許多神經元通過突觸聯繫而形成的。遺傳因素為年幼箇體的突觸聯繫奠定瞭良好的基礎,而網絡中的突觸聯繫又是在內、外界環境因素的影響下,不斷地髮育和完善,因而突觸聯繫便有瞭可塑性和敏感期,而且與一些疾病(如:弱視)的髮病機理密切相關。隨著電生理(尤其是膜片鉗方法)和分子生物學技術的迅猛髮展,近年來對這些課題進行瞭更深入的研究,本文綜述國內外在這方麵的一些新觀唸和所取得的新成果。
시각계통적신경망락시유허다신경원통과돌촉련계이형성적。유전인소위년유개체적돌촉련계전정료량호적기출,이망락중적돌촉련계우시재내、외계배경인소적영향하,불단지발육화완선,인이돌촉련계편유료가소성화민감기,이차여일사질병(여:약시)적발병궤리밀절상관。수착전생리(우기시막편겸방법)화분자생물학기술적신맹발전,근년래대저사과제진행료경심입적연구,본문종술국내외재저방면적일사신관념화소취득적신성과。
Neural network in visual system consists of many neurons through synaptic connections. Genetic factors had well the fundamental synaptic connections in juvenile individuals, however, these synapses have been pro-gressively modifying and perfecting, so the connections of synapses have plasticity, which occurs during the sensitive period of visual development. The plasticity is also related closely with pathogenesis of some diseases (e.g. amblyopia). Following the rapidly developing of electrophysiological (especially the patch-clamp methods) and molecular-biological techniques, this subject has being studied widely. In this short review, the progress of the study will be introduced.