CAJ | 학술논문

目的：探讨中西医结合治疗冠心病心绞痛的临床效果。方法纳入包头市第四医院2012年5月～2013年8月收治的冠心病心绞痛患者120例，按照随机数字法分为2组，治疗组（n＝60）和对照组（n＝60）；2组均给予冠心病二级预防治疗，治疗组在此基础上进行中药和硝酸酯类药物结合治疗，对照组在此基础上仅用硝酸酯类药物治疗，疗程14d。比较2组心绞痛疗效、硝酸甘油减退率和心电图疗效，并进行安全性评价。结果治疗组心绞痛有效率为90.00％，对照组心绞痛有效率71.67％，2组差异有统计学意义（P＜0.05）；治疗组心电图有效率68.33％，对照组心电图有效率48.33％，2组差异有统计学意义（P＜0.05）；治疗组硝酸甘油减停率86.67％，对照组硝酸甘油减停率61.67％，2组差异有统计学意义（P＜0.05）。另外，对照组与治疗组均无不良反应发生。结论对冠心病心绞痛患者在单纯冠心病二级预防基础上采取中西医结合的治疗措施比用硝酸酯类药物的治疗有效率高。
목적：탐토중서의결합치료관심병심교통적림상효과。방법납입포두시제사의원2012년5월～2013년8월수치적관심병심교통환자120례，안조수궤수자법분위2조，치료조（n＝60）화대조조（n＝60）；2조균급여관심병이급예방치료，치료조재차기출상진행중약화초산지류약물결합치료，대조조재차기출상부용초산지류약물치료，료정14d。비교2조심교통료효、초산감유감퇴솔화심전도료효，병진행안전성평개。결과치료조심교통유효솔위90.00％，대조조심교통유효솔71.67％，2조차이유통계학의의（P＜0.05）；치료조심전도유효솔68.33％，대조조심전도유효솔48.33％，2조차이유통계학의의（P＜0.05）；치료조초산감유감정솔86.67％，대조조초산감유감정솔61.67％，2조차이유통계학의의（P＜0.05）。령외，대조조여치료조균무불량반응발생。결론대관심병심교통환자재단순관심병이급예방기출상채취중서의결합적치료조시비용초산지류약물적치료유효솔고。
Objective To explore the clinical effect of traditional Chinese medicine and western medicine in treatment of patients with angina pectoris. Methods 120 cases with angina pectoris admitted in the Fourth Hospital of Baotou City from May 2012 to August 2013 were randomly divided into treatment group (n=60)and control group (n=60). All patients were given secondary prevention of coronary heart disease,and besides this, treatment group were added nitrates medications and traditional Chinese medicine treatment,while control group were only given nitrates medications.The treatment course was 14 days. The efficacy of angina pectoris,nitroglycerin loss rate and electrocardiogram efficacy were compared and the safety were evaluated between two groups. Results The efficacy of angina pectoris in treatment group was 90.00%,while control group was 71.67%,the difference was statistically significant(P<0.05 ). ECG efficiency in treatment group was 68.33%,while control group was 48.33%,the difference was statistically significant(P<0.05 ). The reduction of nitroglycerin was 86.67%,while control group was 61.67%,the difference was statistically significant(P<0.05). In addition,there were no adverse reaction in two groups. Conclusion Compared with nitrates medications,combined Chinese and Western medicine in treatment of patients with angina pectoris on basis of secondary prevention of coronary heart disease has better therapeutically effective rate.