CAJ | 학술논문

目的：探讨首发和复发抑郁症患者执行功能损害情况。方法：采用威斯康星卡片分类测验（WCST）、Stroop 测验、汉密尔顿抑郁量表（HAMD-17）对100例抑郁症患者进行评定，其中首次发病（首发组）患者41例，复发（复发组）患者59例；同时以50名正常人作为对照组进行测评并分析比较。结果：在 WSCT 的总错误数、分类完成数、持续性错误数及持续性应答数、以及 Stroop 色词测验的彩色文字阅读（Stroop-c）时间和彩色文字的色彩阅读（Stroop-cw）正确数上，首发组、复发组与对照组之间差异均有统计学意义（P ﹤0.05或 P ﹤0.01）；Stroop-c 正确数上首发组和复发组之间差异无统计学意义（P ﹥0.05）。结论：无论首发还是复发抑郁症患者均存在明显的执行功能损害，复发者更为显著。
목적：탐토수발화복발억욱증환자집행공능손해정황。방법：채용위사강성잡편분류측험（WCST）、Stroop 측험、한밀이돈억욱량표（HAMD-17）대100례억욱증환자진행평정，기중수차발병（수발조）환자41례，복발（복발조）환자59례；동시이50명정상인작위대조조진행측평병분석비교。결과：재 WSCT 적총착오수、분류완성수、지속성착오수급지속성응답수、이급 Stroop 색사측험적채색문자열독（Stroop-c）시간화채색문자적색채열독（Stroop-cw）정학수상，수발조、복발조여대조조지간차이균유통계학의의（P ﹤0.05혹 P ﹤0.01）；Stroop-c 정학수상수발조화복발조지간차이무통계학의의（P ﹥0.05）。결론：무론수발환시복발억욱증환자균존재명현적집행공능손해，복발자경위현저。
Objective:To explore the impairment of executive function between patients with first-epi-sode and recurrent depression. Method:The Wisconsin card sorting test(WCST),Stroop test,Hamilton de-pression scale( HAMD-17)were used to evaluate 100 depressive patients,in which the first onset patients (first-episode group)41 cases,recurrence patients(recurrent group)59 cases. The results were compared with 50 normal controls. Results:There were statistically significant difference among the first-episode group,the recurrent group and the control group(P ﹤ 0. 05 or P ﹤ 0. 01)on the total number of errors,classification num-ber,perseverative errors,sustained responders of the WCST,time of Stroop-c and correct number of Stroop-cw, but no statistically significant difference on the Stroop-c correct number between the first episode group and the recurrent group(P ﹥ 0. 05). Conclusion:There are significant impairment of executive function in patients with first-episode and recurrent depression,which in recurrent depression patients are more obvious impairment.