CAJ | 학술논문

目的：探讨COPD患者合并肺部真菌感染的危险因素。方法随机选取2011年2月~2013年3月135例COPD患者为研究对象，对其中65例合并肺部真菌感染的病例进行危险因素分析。结果COPD患者合并肺部真菌感染的危险因素有低蛋白血症、住院时间、应用激素和抗生素时间长、机械通气、糖尿病、Ⅱ型呼吸衰竭等有关(P<0．05)，其中长期使用抗生素和激素、低蛋白血症、糖尿病、机械通气、住院时间长、Ⅱ型呼吸衰竭是独立危险因素( P<0．05)。结论合理运用药物，加强营养支持，早期脱机和控制血糖，可减少COPD患者合并肺部真菌感染的发生。
목적：탐토COPD환자합병폐부진균감염적위험인소。방법수궤선취2011년2월~2013년3월135례COPD환자위연구대상，대기중65례합병폐부진균감염적병례진행위험인소분석。결과COPD환자합병폐부진균감염적위험인소유저단백혈증、주원시간、응용격소화항생소시간장、궤계통기、당뇨병、Ⅱ형호흡쇠갈등유관(P<0．05)，기중장기사용항생소화격소、저단백혈증、당뇨병、궤계통기、주원시간장、Ⅱ형호흡쇠갈시독립위험인소( P<0．05)。결론합리운용약물，가강영양지지，조기탈궤화공제혈당，가감소COPD환자합병폐부진균감염적발생。
Objective To investigate the high risk factors of COPD patients complicated with pulmonary fun-gal infection. Methods 135 COPD patients were selected in the study, and 65 cases of them were complicated with pulmonary fungal infection. The high risk factors were analyzed. Results The risk factors for COPD patients compli-cated with pulmonary fungal infections included hypoproteinemia, duration of hospital stay, use of hormones and anti-biotics for a long time, mechanical ventilation, diabetes, and type Ⅱ respiratory failure ( P<0. 05 ) , in which the long-term use of antibiotics and hormones, hypoalbuminemia, diabetes, mechanical ventilation, duration of hospital stay, and type Ⅱ respiratory failure were independent risk factors ( P<0. 05 ) . Conclusion The rational use of medicines, nutritional support, early offline and glycemic control can reduce pulmonary fungal disease in patients with chronic obstructive pulmonary infection.