CAJ | 학술논문

目的：探讨血清C反应蛋白( CRP)检测在小儿支原体肺炎( MP)诊断中的价值。方法128例肺炎患儿按照病原体的不同分为支原体组(45例)、细菌组(43例)、病毒组(40例),并选择健康体检儿童40例作为对照组,比较治疗前四组研究对象血清CRP水平和检测阳性率,并比较不同病情程度MP患儿血清CRP水平和检测阳性率,治疗1周后,比较3组患儿血清CRP水平和检测阳性率。结果血清CRP水平和检测阳性率组间比较,细菌组均明显高于其他3组( P =0．0000),支原体组明显高于病毒组和对照组( P =0．0000),病毒组与对照组比较差异无显著性(P>0．05)。支原体肺炎患儿中伴有全身炎症反应组血清CRP水平和阳性率均高于不伴有全身炎症反应组。治疗1周后,支原体组血清CRP水平高于病毒组(P=0．000),低于细菌组(P=0．0000),CRP检测阳性率支原体组高于病毒组(P=0．0041),低于细菌组(P=0．0223)。结论血清CRP水平检测可作为MP早期诊断和鉴别诊断的重要手段。
목적：탐토혈청C반응단백( CRP)검측재소인지원체폐염( MP)진단중적개치。방법128례폐염환인안조병원체적불동분위지원체조(45례)、세균조(43례)、병독조(40례),병선택건강체검인동40례작위대조조,비교치료전사조연구대상혈청CRP수평화검측양성솔,병비교불동병정정도MP환인혈청CRP수평화검측양성솔,치료1주후,비교3조환인혈청CRP수평화검측양성솔。결과혈청CRP수평화검측양성솔조간비교,세균조균명현고우기타3조( P =0．0000),지원체조명현고우병독조화대조조( P =0．0000),병독조여대조조비교차이무현저성(P>0．05)。지원체폐염환인중반유전신염증반응조혈청CRP수평화양성솔균고우불반유전신염증반응조。치료1주후,지원체조혈청CRP수평고우병독조(P=0．000),저우세균조(P=0．0000),CRP검측양성솔지원체조고우병독조(P=0．0041),저우세균조(P=0．0223)。결론혈청CRP수평검측가작위MP조기진단화감별진단적중요수단。
Objective To explore the clinical value of detection of serum C-reactive protein in the diagnosis of children with mycoplasmal pneumonia. Methods 128 patients with pneumonia were randomly divided into the mycoplasma group (45 cases), the bacterial group (43 cases), and the virus group (40 cases) according to different pathogens, and 40 healthy children were selected as the control group. The level of serum CRP and the positive de-tection rate of the four groups were compared 1 week after the treatment. Results The level of serum CRP and the detection positive rate in the bacterial group were significantly higher than the other three groups (P=0. 0000), and the mycoplasma group was significantly higher than the virus group and the control group ( P=0. 0000 ) . There was no significant difference between the virus group and the control group (P>0. 05). The level of serum CRP and the positive rate were associated with systemic inflammation. The level of serum CRP of the mycoplasma group was higher than that of the virus group at 1st week after treatment (P=0. 000) and lower than that of the bacteria group (P=0. 0000). The positive detection rate of CRP of the mycoplasma group was higher than that of the virus group (P=0. 0041) and lower than that of the bacteria group (P=0. 0223). Conclusion The detection of serum CRP can be used as an important means in the diagnosis of early MP.