CAJ | 학술논문

血管高信号征（FVH）定义为磁共振成像（magnetic resonance imaging，MRI）液体衰减反转恢复序列（fluid-attenuated inver-sion recovery，FLAIR）上大脑半球沿脑沟或脑表面分布的点状、线状或管状的高强度信号。FVH主要出现于急性脑卒中和颅内动脉狭窄-闭塞性疾病患者中，其与血管严重狭窄或闭塞显著相关。FVH的形成机制可能是狭窄或闭塞血管远端侧支血管内的缓慢、紊乱的血流，而非血管内血栓形成。FVH与急性缺血性脑卒中密切相关，不仅可用于诊断颅内动脉狭窄或闭塞病变，而且可预测患者侧支循环的形成情况，从而对于评估其临床病情严重程度及预后具有重要价值。该文总结了FVH的定义、发生率、常见部位、病理生理机制、临床意义等研究进展。
혈관고신호정（FVH）정의위자공진성상（magnetic resonance imaging，MRI）액체쇠감반전회복서렬（fluid-attenuated inver-sion recovery，FLAIR）상대뇌반구연뇌구혹뇌표면분포적점상、선상혹관상적고강도신호。FVH주요출현우급성뇌졸중화로내동맥협착-폐새성질병환자중，기여혈관엄중협착혹폐새현저상관。FVH적형성궤제가능시협착혹폐새혈관원단측지혈관내적완만、문란적혈류，이비혈관내혈전형성。FVH여급성결혈성뇌졸중밀절상관，불부가용우진단로내동맥협착혹폐새병변，이차가예측환자측지순배적형성정황，종이대우평고기림상병정엄중정도급예후구유중요개치。해문총결료FVH적정의、발생솔、상견부위、병리생리궤제、림상의의등연구진전。
Vascular hyperintensities have been defined as focal,tubular,or serpentine hyperintensity relative to gray matter in the sub-arachnoid space or extending into the parenchyma.FVH mainly obtained in the setting of acute stroke and intracranial steno-occlusive disease,and it signicantly associated with severe stenosis or occlusion of blood vessels.The formation mechanism of FVHs may be steno-sis or occlusion of slow blood flow within the vascular distal collateral,not intravascular thrombosis.FVH closely associated with acute ischemic stroke.It is important for the diagnosis of intracranial artery stenosis or occlusion,and can be used to assess the collateral cir-culation and the severity and prognosis of acute ischemic stroke patients.This review summarizes the FVH etiology,common site,patho-physiological mechanisms and clinical significance of research progress.