CAJ | 학술논문

目的：通过中药灌肠联合氟西汀与单用氟西汀治疗肠易激综合征的对照研究，探讨中药联合氟西汀治疗肠易激综合征的疗效。方法：将68例符合罗马Ⅲ诊断标准的肠易激综合征患者随机分为治疗组和对照组各34例，治疗组患者给予中药灌肠联合氟西汀治疗4周，对照组患者给予氟西汀治疗4周，评定临床疗效及不良反应。结果：治疗4周后两组患者临床症状均能明显改善，治疗组患者总有效率为92.62%，对照组患者总有效率为68.56%，治疗组总有效率明显高于对照组，两组患者治疗的有效率差异有显著性(P<0.01)。结论：中药灌肠联合氟西汀与单用氟西汀治疗肠易激综合征疗效好，不良反应小。
목적：통과중약관장연합불서정여단용불서정치료장역격종합정적대조연구，탐토중약연합불서정치료장역격종합정적료효。방법：장68례부합라마Ⅲ진단표준적장역격종합정환자수궤분위치료조화대조조각34례，치료조환자급여중약관장연합불서정치료4주，대조조환자급여불서정치료4주，평정림상료효급불량반응。결과：치료4주후량조환자림상증상균능명현개선，치료조환자총유효솔위92.62%，대조조환자총유효솔위68.56%，치료조총유효솔명현고우대조조，량조환자치료적유효솔차이유현저성(P<0.01)。결론：중약관장연합불서정여단용불서정치료장역격종합정료효호，불량반응소。
Objective:To control study the efficacy of traditional Chinese medicine(TCM) enema combined with fluoxetine and single Fluoxetine in treatment of irritable bowel syndrome, and discuss the efficacy of the former. Methods:According to the criteria of Rome III for irritable bowel syndrome, 68 patients were randomly divided into two groups. The treatment group patients were treated by TCM enema combined with fluoxetine for 4 weeks and the control group patients were treated by fluoxetine for 4 weeks. The clinical ef-ficacy and side effects in the study were evaluated. Results: The clinical symptoms of the two group were significantly improved after 4 weeks' treatment. The total effective rate of treatment group (92. 62% ) was significantly higher than that of control group (68. 56% ), and there was a significant difference between the two groups (P<0. 01). Conclusions: The TCM enema combined with fluoxetine in the treatment of irritable bowel syndrome has good curative effects and less side effects.