中国民康医学
中國民康醫學
중국민강의학
MEDICAL JOURNAL OF CHINSEE PEOPLE HEALTH
2014年
11期
16-17
,共2页
抑郁症%帕罗西汀%度洛西汀
抑鬱癥%帕囉西汀%度洛西汀
억욱증%파라서정%도락서정
Depression%Paroxetine%Duloxetine
目的：探讨帕罗西汀在治疗抑郁症中的临床应用疗效及安全性。方法：选取228例抑郁症患者，随机均分为帕罗西汀组和度洛西汀组两组，均口服给药，治疗6周，以汉密尔顿抑郁量表(HAMD)和汉密顿焦虑量表(HAMA)作为疗效评价指标。结果：帕罗西汀组患者有效率为86.3%，度洛西汀组患者为86.8%，两组患者比较差异无显著性(P>0.05)；帕罗西汀组患者不良反应发生率低于度洛西汀组，差异有统计学意义(P<0.05)。结论：应用帕罗西汀治疗抑郁症临床疗效显著，不良反应率低。
目的：探討帕囉西汀在治療抑鬱癥中的臨床應用療效及安全性。方法：選取228例抑鬱癥患者，隨機均分為帕囉西汀組和度洛西汀組兩組，均口服給藥，治療6週，以漢密爾頓抑鬱量錶(HAMD)和漢密頓焦慮量錶(HAMA)作為療效評價指標。結果：帕囉西汀組患者有效率為86.3%，度洛西汀組患者為86.8%，兩組患者比較差異無顯著性(P>0.05)；帕囉西汀組患者不良反應髮生率低于度洛西汀組，差異有統計學意義(P<0.05)。結論：應用帕囉西汀治療抑鬱癥臨床療效顯著，不良反應率低。
목적：탐토파라서정재치료억욱증중적림상응용료효급안전성。방법：선취228례억욱증환자，수궤균분위파라서정조화도락서정조량조，균구복급약，치료6주，이한밀이돈억욱량표(HAMD)화한밀돈초필량표(HAMA)작위료효평개지표。결과：파라서정조환자유효솔위86.3%，도락서정조환자위86.8%，량조환자비교차이무현저성(P>0.05)；파라서정조환자불량반응발생솔저우도락서정조，차이유통계학의의(P<0.05)。결론：응용파라서정치료억욱증림상료효현저，불량반응솔저。
Objective:To investigate the clinical efficacy and safety of Paroxetine in treatment of depression. Methods:228 ca-ses with depression were randomly divided into duloxetine group and Paroxetine group and were orally treated for 6 weeks. The efifcacy was evaluated with Hamilton depression scale (HAMD) and Hamilton anxiety scale (HAMA). Results: The effective rate of Paroxe-tine group was 86. 3% , while that of duloxetine group was 86. 8% , and the difference was not significant (P>0. 05). The incidence rate of adverse reactions of Paroxetine group was lower that that of duloxetine group, and the difference was statistically significant (P<0. 05). Conclusions: Paroxetine in the treatment of depression has significant effects and less adverse reactions.
