CAJ | 학술논문

目的：：分析某三甲医院住院患者抗深部真菌感染药使用的合理性，了解抗菌药物专项整治活动的效果。方法：利用电子病历系统，采用回顾性调查法，收集医院2010年4月~2012年3月使用过抗深部真菌感染药的住院病例信息，对药物使用合理性进行分析评价。结果：抗深部真菌感染药使用中存在的不合理用药现象主要是在治疗用药时未给予负荷剂量，负荷剂量方式与给药频率的不适宜等；抗菌药物专项整治后总体不合理使用率下降(P<0.05)。结论：通过抗菌药物专项整治活动，该院在一定程度上控制了抗深部真菌感染药的不合理使用现象，但仍需要监管、督导与宣教。
목적：：분석모삼갑의원주원환자항심부진균감염약사용적합이성，료해항균약물전항정치활동적효과。방법：이용전자병력계통，채용회고성조사법，수집의원2010년4월~2012년3월사용과항심부진균감염약적주원병례신식，대약물사용합이성진행분석평개。결과：항심부진균감염약사용중존재적불합리용약현상주요시재치료용약시미급여부하제량，부하제량방식여급약빈솔적불괄의등；항균약물전항정치후총체불합리사용솔하강(P<0.05)。결론：통과항균약물전항정치활동，해원재일정정도상공제료항심부진균감염약적불합리사용현상，단잉수요감관、독도여선교。
Objective:To investigate the rationality of anti-fungal agents for deep fungal infection used in one hospital and the effects of national rectification of antimicrobial drugs. Methods: The retrospective analysis method was used to survey the inpatients administrated anti-fungal agents for deep fungal infection from April 2010 to Mard 2012, and assessed the rationality. Results:The ir-rational utilization of anti-fungal agents for deep fungal infection included loading dosage lack during the treatment,inappropriate loading dosage and administration frequency. The irrational utilization of anti-fungal agents for deep fungal infection was decreased significantly (P<0. 05)after the national rectification of antimicrobial drugs. Conclusion:After the national rectification of antimicrobial drugs, the hospital can amtrol the irrational use of anti-fungal agents to some extent, while still needs more management and education.