中国药师
中國藥師
중국약사
CHINA PHARMACIST
2014年
2期
268-270
,共3页
复方降糖玉液%2型糖尿病%气阴两虚证
複方降糖玉液%2型糖尿病%氣陰兩虛證
복방강당옥액%2형당뇨병%기음량허증
Compound hypoglycemic Yuye oral liquor%Type 2 diabetes mellitus%Deficiency of Qi and Yin
目的：：观察复方降糖玉液联合盐酸二甲双胍和格列美脲治疗2型糖尿病(气阴两虚证)的临床疗效和安全性。方法：80例2型糖尿病(气阴两虚证)患者随机分为观察组和对照组各40例,两组患者均给予盐酸二甲双胍片0.25~0.5 g,po,tid和格列美脲片1~2 mg,po,qd治疗,观察组在此基础上加服复方降糖玉液10 ml,po,tid。治疗12周后观察两组患者空腹血糖(FPG)、餐后2 h血糖(2hPG)、糖化血红蛋白(HbA1c)及中医证候积分变化,评价临床疗效。结果：治疗后两组FPG、2 h PG及HbA1c较治疗前明显下降,且观察组下降明显优于对照组(P<0.05或0.01)；观察组中医证候积分下降明显优于对照组(P<0.01)；观察组临床显效率为47.5%,高于对照组(P<0.05)。结论：复方降糖玉液能有效降低2型糖尿病(气阴两虚证)患者的血糖,显著改善临床症状,安全性好,值得临床推广应用。
目的：：觀察複方降糖玉液聯閤鹽痠二甲雙胍和格列美脲治療2型糖尿病(氣陰兩虛證)的臨床療效和安全性。方法：80例2型糖尿病(氣陰兩虛證)患者隨機分為觀察組和對照組各40例,兩組患者均給予鹽痠二甲雙胍片0.25~0.5 g,po,tid和格列美脲片1~2 mg,po,qd治療,觀察組在此基礎上加服複方降糖玉液10 ml,po,tid。治療12週後觀察兩組患者空腹血糖(FPG)、餐後2 h血糖(2hPG)、糖化血紅蛋白(HbA1c)及中醫證候積分變化,評價臨床療效。結果：治療後兩組FPG、2 h PG及HbA1c較治療前明顯下降,且觀察組下降明顯優于對照組(P<0.05或0.01)；觀察組中醫證候積分下降明顯優于對照組(P<0.01)；觀察組臨床顯效率為47.5%,高于對照組(P<0.05)。結論：複方降糖玉液能有效降低2型糖尿病(氣陰兩虛證)患者的血糖,顯著改善臨床癥狀,安全性好,值得臨床推廣應用。
목적：：관찰복방강당옥액연합염산이갑쌍고화격렬미뇨치료2형당뇨병(기음량허증)적림상료효화안전성。방법：80례2형당뇨병(기음량허증)환자수궤분위관찰조화대조조각40례,량조환자균급여염산이갑쌍고편0.25~0.5 g,po,tid화격렬미뇨편1~2 mg,po,qd치료,관찰조재차기출상가복복방강당옥액10 ml,po,tid。치료12주후관찰량조환자공복혈당(FPG)、찬후2 h혈당(2hPG)、당화혈홍단백(HbA1c)급중의증후적분변화,평개림상료효。결과：치료후량조FPG、2 h PG급HbA1c교치료전명현하강,차관찰조하강명현우우대조조(P<0.05혹0.01)；관찰조중의증후적분하강명현우우대조조(P<0.01)；관찰조림상현효솔위47.5%,고우대조조(P<0.05)。결론：복방강당옥액능유효강저2형당뇨병(기음량허증)환자적혈당,현저개선림상증상,안전성호,치득림상추엄응용。
Objective:To observe the clinical efficacy and safety of compound hypoglycemic Yuye oral liquor combined with metfo-ma and glimepiride in the treatment of type 2 diabetes mellitus ( deficiency of both Qi and Yin) . Methods:Totally 80 type 2 diabetes mellitus patients were randomly divided into the treatment group and the control group with 40 each, both groups were treated with met-formin hydrochloride tablets and glimepiride tablets, the treatment group was given compound hypoglycemic Yuye oral liquor additional-ly, and the treatment duration was 12 weeks. At the end of the treatment, fasting plasma glucose( FPG) , postprandial 2 hours plasma glucose(2hPG), hemoglobin A1c(HbA1c)and traditional Chinese medicine (TCM ) syndrome in the two groups were compared. Re-sults:In both groups, FPG, 2hPG and HbAlc were decreased after the treatment, and the decrease in the treatment group was more notable than that in the control group with statistically significant difference (P<0. 05 or P<0. 01). As for TCM syndrome, the score in the treatment group was lower than that in the control group with statistically significant difference (P<0. 01). The clinical efficien-cy in the treatment group was 47. 5%, that was 22. 5% in the control group, and the difference between the two groups was statistically significant (P<0. 05). Conclusion:Compound hypoglycemic Yuyeoral liquor can reduce the blood glucose in type 2 diabetes mellitus patients( deficiency of Qi and Yin) , and the improvement of clinical symptom is striking with good safety and clinical application value.
