CAJ | 학술논문

目的探讨前列腺囊腺瘤的临床病理学特点,提高对该病的诊断及治疗水平.方法回顾性分析1例病理诊断为前列腺囊腺瘤患者的主要症状,诊治情况,结合文献对该病的临床表现、诊断、病理学特征、治疗及预后进行讨论.结果患者男性,51岁,2008年无明显诱因出现尿频、尿急、排尿困难症状,曾诊断“前列腺炎”,行药物治疗.2012年6月上述症状加重,行彩超检查提示:前列腺肥大并腺体内实性占位；行前列腺穿刺提示:前列腺增生,PINⅡ-Ⅲ级.于外院行TURP治疗,恢复良好.术后1个月开始反复出现血尿.2012年12月7日,急诊以“血尿待查”收入院.入院后完善CT、MRI、膀胱镜等相关检查,诊断为“膀胱颈部占位病变”行经尿道诊断性电切术,将肿物彻底切除.术后病理:前列腺囊腺瘤.组织学特点:前列腺腺体增生,间质纤维组织增生、充血,无细胞异形性,无核分裂像.免疫组化:PSA(+),PSAP(+).结论前列腺囊腺瘤是一种少见的前列腺来源的良性肿瘤,前列腺囊腺瘤在形态学上具有独特的组织结构,多表达PSA和PSAP.
목적 탐토전렬선낭선류적림상병이학특점,제고대해병적진단급치료수평.방법 회고성분석1례병리진단위전렬선낭선류환자적주요증상,진치정황,결합문헌대해병적림상표현、진단、병이학특정、치료급예후진행토론.결과 환자남성,51세,2008년무명현유인출현뇨빈、뇨급、배뇨곤난증상,증진단“전렬선염”,행약물치료.2012년6월상술증상가중,행채초검사제시:전렬선비대병선체내실성점위；행전렬선천자제시:전렬선증생,PINⅡ-Ⅲ급.우외원행TURP치료,회복량호.술후1개월개시반복출현혈뇨.2012년12월7일,급진이“혈뇨대사”수입원.입원후완선CT、MRI、방광경등상관검사,진단위“방광경부점위병변”행경뇨도진단성전절술,장종물철저절제.술후병리:전렬선낭선류.조직학특점:전렬선선체증생,간질섬유조직증생、충혈,무세포이형성,무핵분렬상.면역조화:PSA(+),PSAP(+).결론 전렬선낭선류시일충소견적전렬선래원적량성종류,전렬선낭선류재형태학상구유독특적조직결구,다표체PSA화PSAP.
Objectives To study the clinicopathological characteristics of prostatic cystadenoma (PC) and to improve the level of its diagnosis and treatment.Methods The main syndrome,diagnosis and treatment of a patient who was diagnosed prostatic cystadenoma pathologically were analysised,then the clinical manifestation,diagnosis,pathological characteristic,treatment,and prognosis were discussed referring to the literature.Results The patient was a male aged 51 years,four years ago,he had urinary frequency,urgency,dysuria symptoms with no obvious cause,and was diagnosed "prostatitis",treated with drugs.Six months ago the symptoms aggravated,the color doppler ultrasound showed that prostatic hyperplasia and pace-occupying lesion in the gland,prostatebiopsy showed prostatic hyperplasia,PIN grade Ⅱ to Ⅲ,treated by TURP and have a good recovery.A month after the operation,he appeared recurrent hematuria.On December 7,2012,he was hospitalized in emergency because of hematuria.Then,we did the examination of CT,MRI,and cystoscope,diagnosed as " pace-occupying lesion of the prostate neck",treated with transurethral resection,removed the mass completely.The pathology after operation is prostatic cystadenoma.The histological characteristics were hyperplasia of the prostate gland,mesenchymal tissue fibroplasia and hyperemia,with no atypia of the cell,with no karyokinasis of the nucleus.The immunohistochemistry staining showed positive of PSA and PSAP.Conclusions Prostatic cystadenoma is a rare benign tumor originating in the prostate,with a unique morphological structure,and mostly with the expressions of PSA and PSAP.