按摩与康复医学
按摩與康複醫學
안마여강복의학
Chinese Manipulation & Rehabilitation Medicine
2014年
7期
27-28,29
,共3页
脑梗塞%糖化血红蛋白%C-反应蛋白%相关性
腦梗塞%糖化血紅蛋白%C-反應蛋白%相關性
뇌경새%당화혈홍단백%C-반응단백%상관성
cerebral infarction%glycosylated hemoglobin%C-reactive protein%relevance
目的：探讨脑梗死患者急性期及随访1年后糖化血红蛋白（HbA1c）和血清超敏C-反应蛋白（CRP）的动态变化与其病情严重程度、预后及复发之间的关系。方法：在50例脑梗死患者发病后72小时内、第4~7天和第14天对其血CRP进行测定，以50例健康体检人员的hs-CRP含量作对照，并测定神经功能缺损评分，观察不同大小梗死灶和不同神经功能缺损程度的脑梗死患者血清hs-CRP水平的变化。结果：脑梗死后72小时其血CRP浓度即开始升高，1周左右达高峰，至14天时水平接近对照组水平，并发多脏器功能衰竭者CRP水平最高，大面积梗死患者其hs-CRP水平明显高于小面积梗死患者。结论：血浆CRP是判断脑梗死病情轻重和预后的特异性指标，适时终止或减轻炎症反应损害，可以降低脑梗死的死亡率及并发多脏器衰竭的危险。
目的：探討腦梗死患者急性期及隨訪1年後糖化血紅蛋白（HbA1c）和血清超敏C-反應蛋白（CRP）的動態變化與其病情嚴重程度、預後及複髮之間的關繫。方法：在50例腦梗死患者髮病後72小時內、第4~7天和第14天對其血CRP進行測定，以50例健康體檢人員的hs-CRP含量作對照，併測定神經功能缺損評分，觀察不同大小梗死竈和不同神經功能缺損程度的腦梗死患者血清hs-CRP水平的變化。結果：腦梗死後72小時其血CRP濃度即開始升高，1週左右達高峰，至14天時水平接近對照組水平，併髮多髒器功能衰竭者CRP水平最高，大麵積梗死患者其hs-CRP水平明顯高于小麵積梗死患者。結論：血漿CRP是判斷腦梗死病情輕重和預後的特異性指標，適時終止或減輕炎癥反應損害，可以降低腦梗死的死亡率及併髮多髒器衰竭的危險。
목적：탐토뇌경사환자급성기급수방1년후당화혈홍단백（HbA1c）화혈청초민C-반응단백（CRP）적동태변화여기병정엄중정도、예후급복발지간적관계。방법：재50례뇌경사환자발병후72소시내、제4~7천화제14천대기혈CRP진행측정，이50례건강체검인원적hs-CRP함량작대조，병측정신경공능결손평분，관찰불동대소경사조화불동신경공능결손정도적뇌경사환자혈청hs-CRP수평적변화。결과：뇌경사후72소시기혈CRP농도즉개시승고，1주좌우체고봉，지14천시수평접근대조조수평，병발다장기공능쇠갈자CRP수평최고，대면적경사환자기hs-CRP수평명현고우소면적경사환자。결론：혈장CRP시판단뇌경사병정경중화예후적특이성지표，괄시종지혹감경염증반응손해，가이강저뇌경사적사망솔급병발다장기쇠갈적위험。
To investigate the dynamic change of glycosylated hemoglobin (HbAlc) and serum high sensitivity C-reactive protein (CRP) of patients with cerebral infarction at acute period and after followed-up for 1 year;and the relationship among the change and severity of disease, prog-nosis, recurrence. Methods:In 50 cases of patients with cerebral infarction, serum CRP were tested at paroxysm within 72 hours, the fourth to sev-enth day and the fourteenth day, contrasted by hs-CRP content of 50 cases of healthy people, and tested neural function defect scores, to observe the change of serum hs-CRP level in cerebral infarction patients with different sizes of infarcts and different degrees of neural function defect. Results:From 72 hours after cerebral infarction, the content of serum CRP had begun to increase, and reached the peak at about a week, till the 14th day got close to the level of control group;the CRP level of patients who were complicated with multi-organ exhaustion was the highest, the hs-CRP level of patients with large area infarcts was significantly higher than those with small area infarcts. Conclusion:CRP is a specific index for judging the sever-ity and prognosis of cerebral infarction, timely stop or reduce inflammation damage can reduce the mortality of cerebral infarction and the risk of complicating with multi-organ exhaustion.
