CAJ | 학술논문

目的：探讨利多卡因冷却后治疗烧伤患者创面瘙痒的效果。方法将120例Ⅱ度烧伤愈合过程中创面瘙痒的患者采用随机数字表法分为4组，（室温生理盐水组、低温10℃生理盐水组、室温0.5%利多卡因组、低温10℃0.5％利多卡因组），分别用各自组的溶液按规定计量予以创面喷涂治疗，比较各组间止痒效果、止痒起效时间和缓解间隔时间。结果低温10℃0.5％利多卡因组止痒的有效率达93%，与另外3组比较，差异有统计学意义（P＝0.000）。生理盐水组与0.5%利多卡因组相比较，低温10℃比室温条件下在止痒的起效时间方面有显著效果；低温10℃0.5％利多卡因组在止痒的缓解间隔时间与低温10℃生理盐水比较，差异有统计学意义（P=0.000）。结论利多卡因冷却后喷涂烧伤创面可有效缓解Ⅱ度烧伤患者的瘙痒症状，值得临床推广使用。
목적：탐토리다잡인냉각후치료소상환자창면소양적효과。방법장120례Ⅱ도소상유합과정중창면소양적환자채용수궤수자표법분위4조，（실온생리염수조、저온10℃생리염수조、실온0.5%리다잡인조、저온10℃0.5％리다잡인조），분별용각자조적용액안규정계량여이창면분도치료，비교각조간지양효과、지양기효시간화완해간격시간。결과저온10℃0.5％리다잡인조지양적유효솔체93%，여령외3조비교，차이유통계학의의（P＝0.000）。생리염수조여0.5%리다잡인조상비교，저온10℃비실온조건하재지양적기효시간방면유현저효과；저온10℃0.5％리다잡인조재지양적완해간격시간여저온10℃생리염수비교，차이유통계학의의（P=0.000）。결론리다잡인냉각후분도소상창면가유효완해Ⅱ도소상환자적소양증상，치득림상추엄사용。
Objective To investigate the effect of cooled lidocaine on burn wound itches of patients with grade-II burns. Methods A total of 120 patients of Grade-II burns with wound itching were averagely divided into normal saline at room temperature group (G1), normal saline at 10℃ group (G2), lidocaine at room temperature group (G3), lidocaine at 10℃ group (G4). The antipruritic effect, the antipruritic time and remission intervals before and after the treatment were compared among the groups. Results The antipruritic efficiency of G4 reached 93%, evidently better than that of other three groups (P=0.001). Antipruritic time were longer in both G2 and G4 than that in G1 and G3 and remission intervals in G4 were longer than that in G2 ( P=0.000). Conclusion For burn patients, lidocaine at 10℃can effectively alleviate wound itching and relieve anxiety, which is worth to be promoted clinically.