CAJ | 학술논문

建立摇瓶法测定1,5-戊二胺的正辛醇/水分配系数分析方法。气相色谱法测定正辛醇中1,5-戊二胺含量，离子色谱法测定水相中1,5-戊二胺含量。当正辛醇与水体积比为2：1时，lgPow为-0.38；体积比为1：1时，lgPow为-0.26；体积比为1：2时，lgPow为-0.24；lgPow平均值为-0.3。该方法简单可靠，符合OECD 107要求，适用于1,5-戊二胺的正辛醇/水分配系数的测定。
건립요병법측정1,5-무이알적정신순/수분배계수분석방법。기상색보법측정정신순중1,5-무이알함량，리자색보법측정수상중1,5-무이알함량。당정신순여수체적비위2：1시，lgPow위-0.38；체적비위1：1시，lgPow위-0.26；체적비위1：2시，lgPow위-0.24；lgPow평균치위-0.3。해방법간단가고，부합OECD 107요구，괄용우1,5-무이알적정신순/수분배계수적측정。
The analytical method for determination of the n-octanol/water partition coefficient of 1,5-di-aminopentane by shake flask method was established. The 1,5-diaminopentane in n-octanol was determined by gas chromatography. The 1,5-diaminopentane in water was determined by ion chromatography. When the volumetric ratio of n-octanol/water was 2:1, lgPow was-0.38, the volumetric ratio of n-octanol/water was 1:1, lgPow was -0.26, the volumetric ratio of n-octanol/water was 1:2, lgPow was -0.24. The average value of lgPow was-0.3. The method was simple and reliable, conformed to the requirement of OECD 107, and could be suitable for determination of the n-octanol/water partition coefficient of 1,5-diaminopentane.