中国执业药师
中國執業藥師
중국집업약사
CHINA LICENSED PHARMACIST
2014年
6期
13-15
,共3页
时间差攻击疗法%多重耐药%铜绿假单胞菌%下呼吸道感染%磷霉素%头孢哌酮-舒巴坦
時間差攻擊療法%多重耐藥%銅綠假單胞菌%下呼吸道感染%燐黴素%頭孢哌酮-舒巴坦
시간차공격요법%다중내약%동록가단포균%하호흡도감염%린매소%두포고동-서파탄
Time Difference Attack Therapy%Multiple Drug Resistance%Pseudomonas Aeruginosa%Lower Respira-tory Tract Infection%Fosfomycin%Cefoperazone Sulbactam
目的：探讨时间差疗法治疗下呼吸道多重耐药铜绿假单胞菌感染的疗效。方法：将有多重耐药铜绿假单胞菌感染的病例随机分为实验、对照两组，实验组采用磷霉素与头孢哌酮-舒巴坦时间差攻击疗法，对照组采用磷霉素与头孢哌酮-舒巴坦同时联合疗法。结果：治疗14 d 后，实验组的有效率为85.71%，对照组为65.12%。经χ2检验，有显著性差异（P ＜0.05）。结论：时间差攻击疗法疗效好，为多重耐药铜绿假单胞菌感染提供了一种新的治疗方法。
目的：探討時間差療法治療下呼吸道多重耐藥銅綠假單胞菌感染的療效。方法：將有多重耐藥銅綠假單胞菌感染的病例隨機分為實驗、對照兩組，實驗組採用燐黴素與頭孢哌酮-舒巴坦時間差攻擊療法，對照組採用燐黴素與頭孢哌酮-舒巴坦同時聯閤療法。結果：治療14 d 後，實驗組的有效率為85.71%，對照組為65.12%。經χ2檢驗，有顯著性差異（P ＜0.05）。結論：時間差攻擊療法療效好，為多重耐藥銅綠假單胞菌感染提供瞭一種新的治療方法。
목적：탐토시간차요법치료하호흡도다중내약동록가단포균감염적료효。방법：장유다중내약동록가단포균감염적병례수궤분위실험、대조량조，실험조채용린매소여두포고동-서파탄시간차공격요법，대조조채용린매소여두포고동-서파탄동시연합요법。결과：치료14 d 후，실험조적유효솔위85.71%，대조조위65.12%。경χ2검험，유현저성차이（P ＜0.05）。결론：시간차공격요법료효호，위다중내약동록가단포균감염제공료일충신적치료방법。
Objective:To evaluate the curative effect of time difference attack therapy in the treatment of lower respiratory tract infection caused by multidrug-resistant pseudomonas aeruginosa. Methods: To divide the patients in-fected by multidrug-resistant pseudomonas aeruginosa into experimental group and control group randomly. The experi-mental group took fosfomycin and cefoperazone sulbactam at different time, and control group took the same drugs at the same time. Results: Fourteen days later, the clinical effective incidence of experimental group was 85.71%, while the incidence of control group was 65.21%. By χ2 test , the difference was statistically significant(P < 0.05). Con-clusion: Time difference attack therapy showed a better effect and presented as a new method for the treatment of mul-tidrug-resistant pseudomonas aeruginosa infection.
