中国骨伤
中國骨傷
중국골상
CHINA JOURNAL OF ORTHOPAEDICS AND TRAUMATOLOGY
2014年
6期
518-521
,共4页
复苏术%骨折%休克,出血性%创伤和损伤
複囌術%骨摺%休剋,齣血性%創傷和損傷
복소술%골절%휴극,출혈성%창상화손상
Resuscitation%Fractures%Shock,hemorrhagic%Wounds and injuries
目的:探讨损伤控制性复苏(damage control resuscitation,DCR)在严重骨折合并创伤未控制的失血性休克救治中的临床疗效。方法:回顾性分析2009年1月至2013年5月收治的24例多发骨折合并出血未控制性休克患者的临床资料,其中男18例,女6例;年龄21~48岁,平均(32.5±4.5)岁。术前应用小容量平衡盐液维持收缩压(80~90) mmHg。手术控制出血后快速足量液体复苏,并按照血浆∶悬浮红细胞=1 U∶2 U~1 U∶1 U的比例给予血浆。休克纠正后,维持液体轻度负平衡及电解质酸碱平衡,记录休克纠正前的平衡盐液用量及输血量,动态观察乳酸清除时间、凝血功能、DIC发病率及病死率等指标,延期骨折确定性手术。结果:4例入院后6~18 h抢救无效死亡(急性呼吸窘迫综合征2例,难治性休克2例)。20例在伤后2~6 h休克纠正。平衡盐液平均用量:(4259±268) ml,红细胞悬液(14±2) U,新鲜冰冻血浆(FFP)(800~1600) ml (FFP∶1 U=100 ml),平均(900±300) ml,血小板(PLT)4~6 U。监测凝血功能、电解质无明显异常。24 h内血乳酸值≤2 mmol/L。复苏成功率83.3%(20/24)。结论:实施DCR可明显提高严重骨折合并未控制性创伤失血性休克患者的救治成功率。液体复苏时应当及时补充FFP,纠正凝血功能异常。
目的:探討損傷控製性複囌(damage control resuscitation,DCR)在嚴重骨摺閤併創傷未控製的失血性休剋救治中的臨床療效。方法:迴顧性分析2009年1月至2013年5月收治的24例多髮骨摺閤併齣血未控製性休剋患者的臨床資料,其中男18例,女6例;年齡21~48歲,平均(32.5±4.5)歲。術前應用小容量平衡鹽液維持收縮壓(80~90) mmHg。手術控製齣血後快速足量液體複囌,併按照血漿∶懸浮紅細胞=1 U∶2 U~1 U∶1 U的比例給予血漿。休剋糾正後,維持液體輕度負平衡及電解質痠堿平衡,記錄休剋糾正前的平衡鹽液用量及輸血量,動態觀察乳痠清除時間、凝血功能、DIC髮病率及病死率等指標,延期骨摺確定性手術。結果:4例入院後6~18 h搶救無效死亡(急性呼吸窘迫綜閤徵2例,難治性休剋2例)。20例在傷後2~6 h休剋糾正。平衡鹽液平均用量:(4259±268) ml,紅細胞懸液(14±2) U,新鮮冰凍血漿(FFP)(800~1600) ml (FFP∶1 U=100 ml),平均(900±300) ml,血小闆(PLT)4~6 U。鑑測凝血功能、電解質無明顯異常。24 h內血乳痠值≤2 mmol/L。複囌成功率83.3%(20/24)。結論:實施DCR可明顯提高嚴重骨摺閤併未控製性創傷失血性休剋患者的救治成功率。液體複囌時應噹及時補充FFP,糾正凝血功能異常。
목적:탐토손상공제성복소(damage control resuscitation,DCR)재엄중골절합병창상미공제적실혈성휴극구치중적림상료효。방법:회고성분석2009년1월지2013년5월수치적24례다발골절합병출혈미공제성휴극환자적림상자료,기중남18례,녀6례;년령21~48세,평균(32.5±4.5)세。술전응용소용량평형염액유지수축압(80~90) mmHg。수술공제출혈후쾌속족량액체복소,병안조혈장∶현부홍세포=1 U∶2 U~1 U∶1 U적비례급여혈장。휴극규정후,유지액체경도부평형급전해질산감평형,기록휴극규정전적평형염액용량급수혈량,동태관찰유산청제시간、응혈공능、DIC발병솔급병사솔등지표,연기골절학정성수술。결과:4례입원후6~18 h창구무효사망(급성호흡군박종합정2례,난치성휴극2례)。20례재상후2~6 h휴극규정。평형염액평균용량:(4259±268) ml,홍세포현액(14±2) U,신선빙동혈장(FFP)(800~1600) ml (FFP∶1 U=100 ml),평균(900±300) ml,혈소판(PLT)4~6 U。감측응혈공능、전해질무명현이상。24 h내혈유산치≤2 mmol/L。복소성공솔83.3%(20/24)。결론:실시DCR가명현제고엄중골절합병미공제성창상실혈성휴극환자적구치성공솔。액체복소시응당급시보충FFP,규정응혈공능이상。
Objective:To investigate clinical effects of damage contral resuscitation (DCR) in rescue multiple fracture with hemorrhagic shock. Methods:From January 2009 to May 2013,clinical data of 24 patients suffered from multiple fracture with hemorrhagic shock were retrospectively reviewed. Among them,18 cases were male and 6 cases were female,aged from 21 to 48 years old with an average of (32.5±4.5). Small capacity of balanced salt solution were used to maintain systolic,pres-sure(80-90) mmHg before operation. After control of bleeding with operation,sufficient amount of liquid were rapidly use,and plasma were supplied according to proportion of plasma and red cell suspension (1 U∶2 U~1 U∶1 U). After remedy of shock, fluid infusion were sustained negative balance slightly and keep acid base equilibrium of electrolyte. Dosage of balanced salt solution and blood transfusion before remedy shock were recorded,removal time of lactic acid,coagulation function,incidence and case fatality of DIC were observed. Results:Four patients were died after 6~18 h into hospital (2 cases died for acute res-piratory distress syndrome and 2 cases for irreversible shock ). Twenty patients with shock were corrected at 2~6 h after injury. Dosage of balanced salt solution was(4 259±268) ml,red cell suspension was(14±2) U,fresh frozen plasma was(800~1 600) ml (FFP∶1 U=100 ml) averaged (900±300) ml, blood platelet was 4~6 U. Coagulation function and electrolyte were normal. Lactic acid was less than 2 mmol/L within 24 h,the success rate of recovery was 83.3%(20/24). Conclusion:Performing DCR can obvious improve success rate of remedy serious fracture combined with uncontrolled hemorrhagic shock. Supple-menting FFP when correcting coagulation function should be carry out promptly in fluid resuscitation.