医学研究生学报
醫學研究生學報
의학연구생학보
JOURNAL OF MEDICAL POSTGRADUATE
2014年
6期
648-650
,共3页
曾斌%江翠华(综述)%张吉翔(审校)
曾斌%江翠華(綜述)%張吉翔(審校)
증빈%강취화(종술)%장길상(심교)
免疫球蛋白超家族补体受体%疾病%动物模型
免疫毬蛋白超傢族補體受體%疾病%動物模型
면역구단백초가족보체수체%질병%동물모형
Complement receptor of the immunoglobulin superfamily%Disease%Animal models
免疫球蛋白超家族补体受体( complement receptor of the immunoglobulin superfamily , CRIg)可通过T细胞和细胞因子等调节免疫反应,参与多种疾病发生。文中对动物模型研究CRIg在免疫性肝损伤、肠缺血再灌注损伤、Ⅰ型糖尿病、自身免疫性葡萄膜炎及类风湿关节炎等疾病发生机制中的作用作一综述。
免疫毬蛋白超傢族補體受體( complement receptor of the immunoglobulin superfamily , CRIg)可通過T細胞和細胞因子等調節免疫反應,參與多種疾病髮生。文中對動物模型研究CRIg在免疫性肝損傷、腸缺血再灌註損傷、Ⅰ型糖尿病、自身免疫性葡萄膜炎及類風濕關節炎等疾病髮生機製中的作用作一綜述。
면역구단백초가족보체수체( complement receptor of the immunoglobulin superfamily , CRIg)가통과T세포화세포인자등조절면역반응,삼여다충질병발생。문중대동물모형연구CRIg재면역성간손상、장결혈재관주손상、Ⅰ형당뇨병、자신면역성포도막염급류풍습관절염등질병발생궤제중적작용작일종술。
Complement receptor of the immunoglobulin superfamily ( CRIg) can regulate immune reactions via T cells and cy-tokines and is involved in various diseases .The effect of CRIg on the pathogenesis of immunological liver injury , intestinal ischemia-reperfusion injury , type Ⅰdiabetes mellitus , experimental autoimmune uveoretinitis , and rheumatoid arthritis etc .in animal models of disease are reviewed in this article .