CAJ | 학술논문

脂肪酶在油脂化学、食品工业、有机合成和生物柴油等多个领域有着广泛应用。利用蛋白质工程在分子水平上修饰脂肪酶，可以提高酶活、稳定性和其它催化性质。该文综述了蛋白质工程的基本概念和利用不同方法开发新突变脂肪酶的应用。
지방매재유지화학、식품공업、유궤합성화생물시유등다개영역유착엄범응용。이용단백질공정재분자수평상수식지방매，가이제고매활、은정성화기타최화성질。해문종술료단백질공정적기본개념화이용불동방법개발신돌변지방매적응용。
Lipases have been widely used in oil chemicals,food industry,organic synthesis and biodiesel industry,etc. Protein engineering was used to modify the lipase on a molecular level,for examples,improving the activity,stability and other catalytic properties of lipases. This article reviewed the concepts of protein engineering and the discovery examples of novel lipases and their variants by protein engineering.