CAJ | 학술논문

目的：分析广西壮族自治区2005-2012年流行性乙型脑炎（乙脑）流行特征，评价乙脑控制策略的效果。方法采用描述流行病学方法分析乙脑流行特征，对实施国家扩大免疫规划前后的流行特征进行比较，同时对当地曾经采取的季节性突击接种、普种、应急接种、常规接种免疫及建立监测系统等控制乙脑流行策略的效果进行评价。结果8年间发生乙脑1135例，年平均发病率为0.29/10万；2005-2012年乙脑发病率呈逐年下降趋势，以年均16.80％速度递减。实施扩大免疫规划后发病高峰日（7月1日）延后，流行高峰期（6月2日至7月29日）延长；乙脑疫区范围逐渐缩小；5～7岁儿童发病率至2012年维持在较高水平（1.11/10万～1.79/10万），将成为乙脑高危人群。结论通过监测系统的建立与国家扩大免疫规划策略的实施，消除了乙脑暴发与流行，打破流行周期，发病率降至历史最低水平。
목적：분석엄서장족자치구2005-2012년류행성을형뇌염（을뇌）류행특정，평개을뇌공제책략적효과。방법채용묘술류행병학방법분석을뇌류행특정，대실시국가확대면역규화전후적류행특정진행비교，동시대당지증경채취적계절성돌격접충、보충、응급접충、상규접충면역급건립감측계통등공제을뇌류행책략적효과진행평개。결과8년간발생을뇌1135례，년평균발병솔위0.29/10만；2005-2012년을뇌발병솔정축년하강추세，이년균16.80％속도체감。실시확대면역규화후발병고봉일（7월1일）연후，류행고봉기（6월2일지7월29일）연장；을뇌역구범위축점축소；5～7세인동발병솔지2012년유지재교고수평（1.11/10만～1.79/10만），장성위을뇌고위인군。결론통과감측계통적건립여국가확대면역규화책략적실시，소제료을뇌폭발여류행，타파류행주기，발병솔강지역사최저수평。
Objective ToanalyzetheepidemiccharacteristicsofepidemicencephalitisBinGuangxiZhuangminority autonomousregionduring2005-2012andtoevaluatethecontrolstrategies.Methods Descriptiveepidemiological methods were used to compare epidemic characteristics before and after conducting the national expanded program of immunization.Then all the strategies conducted by local department including seasonal vaccination enhancing,ordinary vaccination,emergencyvaccination,regularvaccinationandmonitorsystemestablishingwereevaluated.Results During 2005 -2012,a total of 1 135 cases were recorded with the annual average incidence of 0.29/100000 and this rate declined every year by 16.80%.Additionally,the incidence rate was seasonal.The peak day (July 1 st)of incidence and the peak period (June 2nd-July 29th)of epidemic were delayed after conducting the expanded program of immunization.The scope of epidemic-stricken area was narrowed down.However,the incidence was still high (1.11 ~1.79/100,000)in the groupofchildrenaged5-7years.Conclusion TheoutbreakandepidemicofepidemicencephalitisBwereterminated owing to the establishment of monitor system and immunity strategy.The epidemic circle was broken and the incidence rate dropped to its lowest level in history.