CAJ | 학술논문

目的：探析沙美特罗/丙酸氟替卡松治疗慢性阻塞性肺病（COPD）的临床疗效。方法将我院2011年12月~2013年3月收治的60例COPD患者作为研究对象，分为试验组和对照组各30例，两组患者在接受常规治疗的同时，试验组患者增加沙美特罗/丙酸氟替卡松的治疗。通过对比两组患者治疗前后的圣乔治呼吸问卷评分（SGRQ评分）、第1秒用力呼气容积（FEV1）、第1秒用力呼气容积占预计值的百分数和最大肺活量（FVC），分析丙酸治疗COPD的效果。结果治疗2个月后，试验组患者SGRQ评分、FEV1、FVC等肺功能指标明显高于对照组，且差异有统计学意义（P＜0.05）。结论丙酸治疗COPD能够改善患者的肺功能，提高患者生活质量。
목적：탐석사미특라/병산불체잡송치료만성조새성폐병（COPD）적림상료효。방법장아원2011년12월~2013년3월수치적60례COPD환자작위연구대상，분위시험조화대조조각30례，량조환자재접수상규치료적동시，시험조환자증가사미특라/병산불체잡송적치료。통과대비량조환자치료전후적골교치호흡문권평분（SGRQ평분）、제1초용력호기용적（FEV1）、제1초용력호기용적점예계치적백분수화최대폐활량（FVC），분석병산치료COPD적효과。결과치료2개월후，시험조환자SGRQ평분、FEV1、FVC등폐공능지표명현고우대조조，차차이유통계학의의（P＜0.05）。결론병산치료COPD능구개선환자적폐공능，제고환자생활질량。
Objective To evaluate the clinical efficacy of Salmeterol/fluticasone propionate in the treatment of COPD. Methods60 patients with COPD were recruited in the study from Dec 2011 to Mar 2013 in our hospital. Of the 60 included patients, 30 in the control group were given regular treatment and other 30 case were give Salmeterol/fluticasone propionate on the basis of regular treatment. The SGRQ score, FEV1 and FVC were measured and compared between the groups to evaluate the clinical efficacy of Salmeterol/fluticasone propionate. ResultsAfter 2 months treatment, the SGRQ score, FEV1, FVC were much higher in the treatment group than that of control, with statistical difference(P<0.05). ConclusionSalmeterol/fluticasone can significant improve the lung function and life quality of patients with COPD.