CAJ | 학술논문

目的：探讨抗生素和益生菌制剂治疗腹泻型肠易激综合征的临床效果。方法选取本院2011年10月～2013年10月诊治的腹泻型肠易激综合征患者128例，根据治疗方案分为两组，64例患者采用益生菌制剂治疗为对照组，64例患者采用抗生素和益生菌制剂治疗为观察组，疗程8周，在治疗前后不同时间点给予患者症状评分，比较两组患者的治疗效果。结果观察组患者在治疗2周、4周、6周、8周时症状评分均明显低于对照组，观察组患者总有效率（98.44%）明显高于对照组（87.50%），差异均有统计学意义（P＜0.05）。结论抗生素和益生菌制剂是治疗腹泻型肠易激综合征的有效药物，可明显改善患者的临床病症，显著提高疾病的治疗效果。
목적：탐토항생소화익생균제제치료복사형장역격종합정적림상효과。방법선취본원2011년10월～2013년10월진치적복사형장역격종합정환자128례，근거치료방안분위량조，64례환자채용익생균제제치료위대조조，64례환자채용항생소화익생균제제치료위관찰조，료정8주，재치료전후불동시간점급여환자증상평분，비교량조환자적치료효과。결과관찰조환자재치료2주、4주、6주、8주시증상평분균명현저우대조조，관찰조환자총유효솔（98.44%）명현고우대조조（87.50%），차이균유통계학의의（P＜0.05）。결론항생소화익생균제제시치료복사형장역격종합정적유효약물，가명현개선환자적림상병증，현저제고질병적치료효과。
ObjectiveTo investigate the clinical effect of antibiotics and probiotics in treatment for IBS-D. Methods128 patients with IBS-D were selected in hospital from October 2011 to October 2013. According to treatment, the patients were divided into two groups. 64 patients treated probiotics as control group. 64 patients treated antibiotics and probiotics as observation group. Course of treatment was 8 weeks. Symptom scores were finished in different time points before and after treatment. Therapeutic effect was compared between two groups. Results Symptom scores at 2 weeks,4 weeks,6 weeks,8 weeks in observation group were significantly lower than control group. Total efficiency in observation group(98.44%) was significantly higher than control group(87.50%). Differences were statistically significant(P<0.05).Conclusion Antibiotics and probiotics are effective drugs in treatment for IBS-D, which can significantly improve clinical symptoms and improve therapeutic effect.