中国医药科学
中國醫藥科學
중국의약과학
CHINA MEDICINE AND PHARMACY
2014年
10期
17-19
,共3页
鼻息肉%呼吸道合胞病毒%腺病毒%免疫组织化学
鼻息肉%呼吸道閤胞病毒%腺病毒%免疫組織化學
비식육%호흡도합포병독%선병독%면역조직화학
Nasal polyps%RSV%ADV%Immunohistochemical analysis
目的：探讨呼吸道合胞病毒（RSV）、腺病毒（ADV）在鼻息肉组织中的表达及其与鼻息肉发病的相关性。方法利用免疫组织化学方法检测40例鼻息肉患者组织中RSV、ADV的表达情况，另检测20例鼻中隔偏曲患者正常的鼻黏膜组织中RSV、ADV表达情况。结果正常鼻黏膜中的RSV、ADV表达的阳性率分别为35.0%、35.0%；鼻息肉组织中RSV的阳性表达率为67.5%，ADV的阳性表达率为75.0%。结论 RSV、ADV感染与鼻息肉的发病密切相关。
目的：探討呼吸道閤胞病毒（RSV）、腺病毒（ADV）在鼻息肉組織中的錶達及其與鼻息肉髮病的相關性。方法利用免疫組織化學方法檢測40例鼻息肉患者組織中RSV、ADV的錶達情況，另檢測20例鼻中隔偏麯患者正常的鼻黏膜組織中RSV、ADV錶達情況。結果正常鼻黏膜中的RSV、ADV錶達的暘性率分彆為35.0%、35.0%；鼻息肉組織中RSV的暘性錶達率為67.5%，ADV的暘性錶達率為75.0%。結論 RSV、ADV感染與鼻息肉的髮病密切相關。
목적：탐토호흡도합포병독（RSV）、선병독（ADV）재비식육조직중적표체급기여비식육발병적상관성。방법이용면역조직화학방법검측40례비식육환자조직중RSV、ADV적표체정황，령검측20례비중격편곡환자정상적비점막조직중RSV、ADV표체정황。결과정상비점막중적RSV、ADV표체적양성솔분별위35.0%、35.0%；비식육조직중RSV적양성표체솔위67.5%，ADV적양성표체솔위75.0%。결론 RSV、ADV감염여비식육적발병밀절상관。
Objective To investigate the expression of RespiratorySyncytialVirus(RSV), Adenovirus(ADV)in nasal polyps tissue,andtheir relevance to the pathog enesis of human nasal polyps.Methods Immunohistochemistry was used to detect the expression ofRespiratorySyncytialVirus(RSV),Adenovirus(ADV),in excisiona l nasal polyps t issue from 40 patients with nasal polyps. In addition,the ex pression of RSV,ADV were also detected in normal nasal mucosa from 20 patients with the nasal septum deviation.ResultsIn the normal nasal mucosa,the positive rates of RSV,ADVexpression were 35.0%,35.0% respectively.In the nasal polyps tissues,RSV positive rate was 67.5%,ADV positive rate was 75.0%. ConclusionRSV and ADV infectionpostive expression suggest that they closely correlate with the pathogenesis ofhuman nasal polyps.
