CAJ | 학술논문

葛根素是首个在葛根中被提炼并识别的主要异黄酮成分，具有众多的生物学活性。由于其对心肌、血管上皮及神经细胞具有保护作用而被用于心脑血管疾病的临床治疗。近年来多项研究发现葛根素对多种细胞还具有抗凋亡作用，并且发挥这一作用的途径几乎涵盖所有导致细胞凋亡途径。本文就相关研究所揭示的葛根素抗凋亡作用及其可能途径作一综述。
갈근소시수개재갈근중피제련병식별적주요이황동성분，구유음다적생물학활성。유우기대심기、혈관상피급신경세포구유보호작용이피용우심뇌혈관질병적림상치료。근년래다항연구발현갈근소대다충세포환구유항조망작용，병차발휘저일작용적도경궤호함개소유도치세포조망도경。본문취상관연구소게시적갈근소항조망작용급기가능도경작일종술。
Puerarin is the main composition of isoflavones, which was isolated from radix puerariae and identified, and has many biological activities. Because of its protective effects of myocardium, vascular epithelial cells and nerve cells, the puerarin has been used to treat the cardiovascular and cerebrovascular diseases. In recent years, it has been found that puerarin has anti-apoptotic effects on a variety of cells, and given the role by almost all ways led to apoptosis. In this paper, the anti-apoptosis functions and those possible signaling pathway of puerarin were reviewed.