中华临床医师杂志(电子版)
中華臨床醫師雜誌(電子版)
중화림상의사잡지(전자판)
CHINESE JOURNAL OF CLINICIANS(ELECTRONIC VERSION)
2014年
11期
2124-2126
,共3页
孛茹婷%杨文君%霍正浩%陈志强
孛茹婷%楊文君%霍正浩%陳誌彊
패여정%양문군%곽정호%진지강
前列腺肿瘤%雄激素类%指长比
前列腺腫瘤%雄激素類%指長比
전렬선종류%웅격소류%지장비
Prostatic neoplasms%Androgens%Digit ratio
指长比(2D∶4D)即食指与无名指长度之比,具有性别差异,是围产期激素水平的一个重要指标。围产期激素活动会影响个体发育过程中某些心理、行为学特征及某些心血管疾病。近来2D∶4D与某些疾病患病率等之间的研究逐步成为热点。在此讨论2D∶4D与激素依赖疾病的研究,特别是2D∶4D与前列腺癌其关系的研究同样适用于其他疾病。
指長比(2D∶4D)即食指與無名指長度之比,具有性彆差異,是圍產期激素水平的一箇重要指標。圍產期激素活動會影響箇體髮育過程中某些心理、行為學特徵及某些心血管疾病。近來2D∶4D與某些疾病患病率等之間的研究逐步成為熱點。在此討論2D∶4D與激素依賴疾病的研究,特彆是2D∶4D與前列腺癌其關繫的研究同樣適用于其他疾病。
지장비(2D∶4D)즉식지여무명지장도지비,구유성별차이,시위산기격소수평적일개중요지표。위산기격소활동회영향개체발육과정중모사심리、행위학특정급모사심혈관질병。근래2D∶4D여모사질병환병솔등지간적연구축보성위열점。재차토론2D∶4D여격소의뢰질병적연구,특별시2D∶4D여전렬선암기관계적연구동양괄용우기타질병。
Digit ratio (2D∶4D) denotes the relative length of the 2nd and 4th digits. The ratio is considered to be a proxy marker for prenatal exposure and sensitivity to sexual hormones, which can be genetically influenced. The influence of prenatal hormone exposure can reflect on psychological traits, athletic performance and diseases such as cardiovascular. Recently there has been a great deal of interest in 2D:4D and risk of disease in adulthood. Here we briefly discussed the rationale behind the use of 2D∶4D in studies of hormone-related diseases in later life-with particular regard to cancers of the prostate. Though the focus of this article was on prostate cancer, the rationale presented applied equally to other diseases.