CAJ | 학술논문

目的：探讨初诊2型糖尿病患者血清超敏C反应蛋白水平及相关因素。方法：选择50例初诊2型糖尿病患者及50例健康体检者作为研究对象，比较两组患者血清hs-CRP 水平，并分析2型糖尿病患者hs-CRP相关因素。结果：初诊2型糖尿病患者BMI、腰围、SBP、DBP、TC、TG及hs-CRP水平均明显高于健康对照组，差异有统计学意义（ P＜0．05）；2型糖尿病患者BMI、腰围、FBG、HOMA-IR与血清CRP 水平呈正相关性（P＜0．05），HOMA-B与血清CRP 水平呈负相关性（P＜0．05）。结论：血清hs-CRP 水平在初诊2型糖尿病患者明显升高，可能与超重或肥胖及胰岛素抵抗、胰岛β细胞功能衰退相关。
목적：탐토초진2형당뇨병환자혈청초민C반응단백수평급상관인소。방법：선택50례초진2형당뇨병환자급50례건강체검자작위연구대상，비교량조환자혈청hs-CRP 수평，병분석2형당뇨병환자hs-CRP상관인소。결과：초진2형당뇨병환자BMI、요위、SBP、DBP、TC、TG급hs-CRP수평균명현고우건강대조조，차이유통계학의의（ P＜0．05）；2형당뇨병환자BMI、요위、FBG、HOMA-IR여혈청CRP 수평정정상관성（P＜0．05），HOMA-B여혈청CRP 수평정부상관성（P＜0．05）。결론：혈청hs-CRP 수평재초진2형당뇨병환자명현승고，가능여초중혹비반급이도소저항、이도β세포공능쇠퇴상관。
Objective:To investigate levels and related factors of serum high sensitivity C-reactive pro-tein(hs-CRP) in newly diagnosed type 2 diabetic patients.Method:50 cases of newly diagnosed type 2 di-abetic patients and 50 healthy volunteers were included in this study , the serum hs-CRP levels in two groups and hs-CRP relevant factors in type 2 diabetes were analyzed.Result:The BMI, waist circumference ,SBP, DBP,TC,TG and hs-CRP in patients with type 2 diabetes were significantly higher than those in control group, the difference was statistically significant ( P<0.05); In type 2 diabetes patients ,the BMI, waist circumference , FBG, HOMA-IR and serum CRP levels were of positively connection ( P<0.05) , HOMA-B and serum CRP levels was of negatively connection ( P <0.05) .Conclusion:The serum hs-CRP levels are significantly elevated in patients with newly diagnosed type 2 diabetes , and may be associated with over-weight or obesity and insuLin resistance , pancreatic B-cell function decline .