河北医学
河北醫學
하북의학
HEBEI MEDICINE
2014年
10期
1601-1604
,共4页
血清IL-23%血浆脑钠肽%慢性心力衰竭%预后
血清IL-23%血漿腦鈉肽%慢性心力衰竭%預後
혈청IL-23%혈장뇌납태%만성심력쇠갈%예후
Serum IL-23%Plasma brain natriuretic peptide%Chronic heart failure%Prognosis
目的:探究分析血清IL-23联合血浆脑钠肽检测对判断慢性心力衰竭患者预后的指标及影响。方法:选取我院自2011年5月至2013年5月收治的慢性心力衰竭患者51例,作为临床研究对象,作为试验组。选取同期51名健康体检者,作为对照组。检测试验组患者与对照组健康人血清IL-23、血浆脑钠肽含量,并比较它们的阳性检测率。结果:试验组患者血清IL-23、血浆脑钠肽阳性检出率(96.08%、94.12%)高于对照组(7.84%、9.80%),P<0.05;试验组患者51例中心功能改善及心衰在住院患者即存活患者共48例,BNP 水平与YNHA分级之间呈正相关且差异明显( P<0.05),BNP 水平升高患者的死亡率也随之增加。结论:血清IL-23联合血浆脑钠肽检测对判断慢性心力衰竭患者预后有一定优势,其变化能能反映出慢性心衰患者的心脏功能分级情况及病情进展,更准确地判断预后,对患者病情的评价具有一定的意义,值得临床推广使用。
目的:探究分析血清IL-23聯閤血漿腦鈉肽檢測對判斷慢性心力衰竭患者預後的指標及影響。方法:選取我院自2011年5月至2013年5月收治的慢性心力衰竭患者51例,作為臨床研究對象,作為試驗組。選取同期51名健康體檢者,作為對照組。檢測試驗組患者與對照組健康人血清IL-23、血漿腦鈉肽含量,併比較它們的暘性檢測率。結果:試驗組患者血清IL-23、血漿腦鈉肽暘性檢齣率(96.08%、94.12%)高于對照組(7.84%、9.80%),P<0.05;試驗組患者51例中心功能改善及心衰在住院患者即存活患者共48例,BNP 水平與YNHA分級之間呈正相關且差異明顯( P<0.05),BNP 水平升高患者的死亡率也隨之增加。結論:血清IL-23聯閤血漿腦鈉肽檢測對判斷慢性心力衰竭患者預後有一定優勢,其變化能能反映齣慢性心衰患者的心髒功能分級情況及病情進展,更準確地判斷預後,對患者病情的評價具有一定的意義,值得臨床推廣使用。
목적:탐구분석혈청IL-23연합혈장뇌납태검측대판단만성심력쇠갈환자예후적지표급영향。방법:선취아원자2011년5월지2013년5월수치적만성심력쇠갈환자51례,작위림상연구대상,작위시험조。선취동기51명건강체검자,작위대조조。검측시험조환자여대조조건강인혈청IL-23、혈장뇌납태함량,병비교타문적양성검측솔。결과:시험조환자혈청IL-23、혈장뇌납태양성검출솔(96.08%、94.12%)고우대조조(7.84%、9.80%),P<0.05;시험조환자51례중심공능개선급심쇠재주원환자즉존활환자공48례,BNP 수평여YNHA분급지간정정상관차차이명현( P<0.05),BNP 수평승고환자적사망솔야수지증가。결론:혈청IL-23연합혈장뇌납태검측대판단만성심력쇠갈환자예후유일정우세,기변화능능반영출만성심쇠환자적심장공능분급정황급병정진전,경준학지판단예후,대환자병정적평개구유일정적의의,치득림상추엄사용。
Objective:To explore the influence of serum IL-23 combined with plasma brain natriuretic peptide on judging the prognosis indicators of patients with chronic heart failure ( CHF) .Method:51 patients with CHF treated in our hospital from May 2011 to May 2013 were selected as the clinical research object , as the experimental group .And selected 51 healthy subjects as control group in the same period .Detected the content of serum IL-23 and plasma brain natriuretic peptide in the two groups and compared the positive de-tection rate.Result:The possitive detection rate of serum IL-23 and plasma brain natriuretic peptide of ex-perimental group (96.08%,94.12%) were significantly higher than those in control group (7.84%,9.80%) (P<0.05);In experimental group (51 cases),there were 48 patients had their cardiac function improved and survived ,BNP level had positive correlation with YNHA grading , difference was significant ( p<0.05 ) , and mortality increased when BNP level increased .Conclusion:Serum IL-23 combined with plasma brain natri-uretic peptide has certain advantages in judging the prognosis of patients with CHF , which can reflect cardiac function classfication and progressive disease and more accurate ,have certain significance in evaluating path-ogenetic condition of the patients , it’ s worthy of being applied in clinic .