CAJ | 학술논문

目的：探讨降钙素原(PCT)联合超敏C反应蛋白(hs-CRP)在社区获得性肺炎诊断的临床意义。方法：将本院2011年3月-2014年3月40例社区获得性肺炎患者设为观察组，同期健康体检人员40例设为对照组，使用固相夹心法酶联免疫吸附实验(ELISA)比较两组PCT、hs-CRP浓度差异，同时对PCT、hs-CRP两个指标做线性相关性分析。结果：(1)观察组PCT水平为(1.09±0.33)μg/L，hs-CRP水平为(4.88±0.19)mg/L，对照组分别为(0.32±0.02)μg/L，(1.45±0.04) mg/L，两组比较具显著统计学差异(P<0.01)，观察组明显高于对照组；(2)观察组血清PCT 和hs-CRP水平呈正相关(r=0.924 P=0.011＜0.05)。结论：降钙素原联合超敏C反应蛋白对社区获得性肺炎的诊断，以及预后的评估，具有较高的应用价值。
목적：탐토강개소원(PCT)연합초민C반응단백(hs-CRP)재사구획득성폐염진단적림상의의。방법：장본원2011년3월-2014년3월40례사구획득성폐염환자설위관찰조，동기건강체검인원40례설위대조조，사용고상협심법매련면역흡부실험(ELISA)비교량조PCT、hs-CRP농도차이，동시대PCT、hs-CRP량개지표주선성상관성분석。결과：(1)관찰조PCT수평위(1.09±0.33)μg/L，hs-CRP수평위(4.88±0.19)mg/L，대조조분별위(0.32±0.02)μg/L，(1.45±0.04) mg/L，량조비교구현저통계학차이(P<0.01)，관찰조명현고우대조조；(2)관찰조혈청PCT 화hs-CRP수평정정상관(r=0.924 P=0.011＜0.05)。결론：강개소원연합초민C반응단백대사구획득성폐염적진단，이급예후적평고，구유교고적응용개치。
Objective: to discuss the clinical significance of procalcitonin (PCT)combined hypersensitive c-reactive protein (hs-CRP)in the diagnosis of Community-acquired pneumonia. Methods: 40 cases of senile pneumonia patients in our hospital during March 2011 to March 2013 were supposed as observation group, 40 cases of healthy medical examiner in the the corresponding period as control group, compared PCT, hs-CRP concentration difference of two groups by using solid-phase sandwich method enzyme-linked immunosorbent (ELISA), of PCT and hs CRP, took linear correlation analysis of the two index at the same time.Results: (1)the PCT level of the observation group was(1.09±0.33)μg/L, hs-CRP level was (4.88±0.19) mg/L, respectively (0.32±0.02)μg/L,and(1.45±0.04)mg/L in the control group, the two groups have statistical y significant differences by comparison (P<0.01), the observation group was significantly higher than the control group; (2)serum PCT and hs-CRP levels were positively correlated in the observation group (r=0.924 P=0.011<0.05).Conclusion:procalcitonin combined hypersensitive c-reactive protein had higher application value in the diagnosis of Community-acquired pneumonia and the assessment of prognosis.