CAJ | 학술논문

目的：对抗生素降阶梯疗法与传统抗生素治疗老年肺炎疗效及安全性进行分析比较。方法80例老年肺炎患者按照随机数表法分为观察组和对照组，各40例，对照组给予传统抗生素治疗，观察组给予抗生素降阶梯疗法治疗，比较两组患者的二次感染发生率、治疗效果和住院时间等指标的差异。结果观察组患者临床治疗的总有效率(90.0%)高于对照组(75%)，二次感染率(7.5%)低于对照组(27.5%)，差异具有统计学意义(P<0.05)；观察组静脉应用抗生素时间、感染控制时间、平均住院时间均低于对照组，差异有统计学意义(P<0.05)。结论抗生素降阶梯疗法治疗老年肺炎安全有效，促进了患者恢复。
목적：대항생소강계제요법여전통항생소치료노년폐염료효급안전성진행분석비교。방법80례노년폐염환자안조수궤수표법분위관찰조화대조조，각40례，대조조급여전통항생소치료，관찰조급여항생소강계제요법치료，비교량조환자적이차감염발생솔、치료효과화주원시간등지표적차이。결과관찰조환자림상치료적총유효솔(90.0%)고우대조조(75%)，이차감염솔(7.5%)저우대조조(27.5%)，차이구유통계학의의(P<0.05)；관찰조정맥응용항생소시간、감염공제시간、평균주원시간균저우대조조，차이유통계학의의(P<0.05)。결론항생소강계제요법치료노년폐염안전유효，촉진료환자회복。
Objective To analyze and compare effect and safety of antibiotic de-escalation therapy and conventional antibiotic in treatment of elderly pneumonia. Methods Diveided 80 cases of elderly pneumonia patients into observation group and control group according to a random number table method, 40 cases in each group, control group was treated with traditional antibiotic therapy, observation group was treated with antibiotic de-escalation therapy, the incidence of secondary infection, curative effect, hospitalization and so on were compared in two groups. Results Total effective rate of observation group(90.0%)was higher than that of the control group(75%), incidence of secondary infection(7.5%) was lower than that of the control group(27.5%), there was statistical significance(P<0.05), intravenous antibiotics time, infection control and hospitalization time of observation group were lower than control group, differences were statistically significant(P<0.05). Conclusion Antibiotic de-escalation therapy in the treatment of elderly pneumonia is safe and effective and can promote the recovery of patients.