CAJ | 학술논문

目的：探讨米非司酮联合利凡诺(乳酸依沙丫啶)终止中期妊娠的临床疗效。方法90例14~24周终止妊娠孕妇资料,随机分为观察组及对照组,各45例,两组患者均采用羊膜腔内注射利凡诺100 mg引产,观察组患者同时口服米非司酮150 mg,比较两组患者产程、用药至规律宫缩时间,同时记录产后24 h内出血量及胎盘、胎膜残留、引产成功情况。结果观察组产程时间为(7.23±1.26)h,用药至规律宫缩时间为(25.44±8.74)h均短于对照组,比较差异有统计学意义(P<0.05)；观察组24 h内出血量为(63.55±31.57)ml,引产成功率为95.6%,胎盘胎膜残留率为20.0%,与对照组患者比较差异有统计学意义(P<0.05)。结论米非司酮联合利凡诺终止中期妊娠产程短、孕妇术后不良反应发生率低,方法简单安全,值得在临床推广。
목적：탐토미비사동연합리범낙(유산의사아정)종지중기임신적림상료효。방법90례14~24주종지임신잉부자료,수궤분위관찰조급대조조,각45례,량조환자균채용양막강내주사리범낙100 mg인산,관찰조환자동시구복미비사동150 mg,비교량조환자산정、용약지규률궁축시간,동시기록산후24 h내출혈량급태반、태막잔류、인산성공정황。결과관찰조산정시간위(7.23±1.26)h,용약지규률궁축시간위(25.44±8.74)h균단우대조조,비교차이유통계학의의(P<0.05)；관찰조24 h내출혈량위(63.55±31.57)ml,인산성공솔위95.6%,태반태막잔류솔위20.0%,여대조조환자비교차이유통계학의의(P<0.05)。결론미비사동연합리범낙종지중기임신산정단、잉부술후불량반응발생솔저,방법간단안전,치득재림상추엄。
Objective To investigate clinical effect of mifepristone and ethacridine lactate(rivanol) in terminating mid-pregnancy. Methods Divided 90 cases of termination of pregnancy from 14 to 24 weeks pregnant data into observation group and control group, 45 cases in each group, two groups were treated with intra-amniotic injection of 100 mg abortion rivanol, observed group added mifepristone 150 mg, birth process, medication to regular contractions time of two groups were compared, while recording 24 h postpartum hemorrhage volume and placenta, fetal membranes residues, successful induction conditions. Results Birth process and medicine to time contractions of observation group were shorter than control group, the difference was statistically significant(P<0.05); postpartum hemorrhage in patients less 24 h observation group, high success rate of abortion, low fetal membranes residues, compared with patients in the control group differences. were statistically significant(P<0.05). Conclusion Mifepristone combined with rivanol in terminating mid-pregnancy has a short birth process, low incidence of adverse reactions, so it is worthy of clinical promotion.