CAJ | 학술논문

目的：探讨尿微量清蛋白检测对诊断早期糖尿病肾病的临床意义。方法回顾性分析2011年8月至2013年2月化州市中医院收治的50例糖尿病肾病患者（观察组）和50例健康体检者（对照组）的临床资料。结果观察组患者尿微量清蛋白含量和阳性率均明显比对照组高，差异有统计学意义（P＜0．05），但观察组男性患者和女性患者阳性率差异无统计学意义（ P＞0．05）；病程大于12年患者的尿微量清蛋白含量和阳性率均明显比病程0～6、＞6～12年患者高，差异有统计学意义（ P＜0．05），且病程0～6、＞6～12年患者尿微量清蛋白和阳性率比较，差异均有统计学意义（P＜0．05）。结论尿微量清蛋白检测能够为临床早期发现、诊断和治疗糖尿病肾病提供有效依据。
목적：탐토뇨미량청단백검측대진단조기당뇨병신병적림상의의。방법회고성분석2011년8월지2013년2월화주시중의원수치적50례당뇨병신병환자（관찰조）화50례건강체검자（대조조）적림상자료。결과관찰조환자뇨미량청단백함량화양성솔균명현비대조조고，차이유통계학의의（P＜0．05），단관찰조남성환자화녀성환자양성솔차이무통계학의의（ P＞0．05）；병정대우12년환자적뇨미량청단백함량화양성솔균명현비병정0～6、＞6～12년환자고，차이유통계학의의（ P＜0．05），차병정0～6、＞6～12년환자뇨미량청단백화양성솔비교，차이균유통계학의의（P＜0．05）。결론뇨미량청단백검측능구위림상조기발현、진단화치료당뇨병신병제공유효의거。
Objective To investigate the clinical significance of urinary microalbumin in the diagnosis of early diabetic nephropathy .Methods Clinical data of 50 patients with diabetic nephropathy treated in this hospital from August 2011 to February 2013 were retrospectively analyzed .Results Level and positive rate of urinary microalbu-min in observation group were significantly higher than that of the control group (P<0 .05) ,but there was no signifi-cant difference of positive rate between men and women in observation group (P>0 .05) .Urinary microalbumin con-centration and positive rate of patients with disease course at least 12 years were significantly higher than patients with disease course less than 12 years (P<0 .05) ,and but the differences between patients with disease course of 0-6 years and 6-12 years were significant (P<0 .05) .Conclusion Detection of urinary microalbumin could provide ef-fective basis for the early diagnosis and treatment of diabetic nephropathy .