CAJ | 학술논문

目的：通过医院青霉素类抗菌药物应用现状分析，探讨合理使用青霉素类抗菌药物方法。方法：随机抽取2010年和2011年的出院病历各1000份，包括内科、外科、五官科、儿科及其他科室，各200份；实施规范化用药制度前的2010年份为对照组)，实施规范化用药制度后的2011年份为观察组，比较两组青霉素类应用构成比、不当使用、不科学配伍及不规范给药等情况。结果：实施规范化用药制度后，除内科、五官科，其他科室青霉素类抗菌药物应用构成比显著下降；青霉素类抗菌药物联用情况明显减少；青霉素类抗菌药物的不合理使用情况明显减少( P<0.05)。结论：青霉素类抗菌药物的临床应用，关键在于对症用药、配伍禁忌、皮试试验、配置因素、用药途径及间隔等因素，严格执行规范化用药流程，必能改善抗菌药物应用现状。
목적：통과의원청매소류항균약물응용현상분석，탐토합리사용청매소류항균약물방법。방법：수궤추취2010년화2011년적출원병력각1000빈，포괄내과、외과、오관과、인과급기타과실，각200빈；실시규범화용약제도전적2010년빈위대조조)，실시규범화용약제도후적2011년빈위관찰조，비교량조청매소류응용구성비、불당사용、불과학배오급불규범급약등정황。결과：실시규범화용약제도후，제내과、오관과，기타과실청매소류항균약물응용구성비현저하강；청매소류항균약물련용정황명현감소；청매소류항균약물적불합리사용정황명현감소( P<0.05)。결론：청매소류항균약물적림상응용，관건재우대증용약、배오금기、피시시험、배치인소、용약도경급간격등인소，엄격집행규범화용약류정，필능개선항균약물응용현상。
Objective: To observe the rational use-methods of Penicil in by the analysis of our hospital’s application status. Methods: The clinical materials of 2000 patients were extracted from 2010 to 2011, and divided into two groups by the difference of dosing system to compare the constituent ratio of Penicil in, improper use, unscientific compatibility and abnormal administration. Each Group was divided into five departments, and the observation group was treated by standardized dosing system. Results: The constituent ratio (except internal medicine and E.N.T. department), conjunction, and irrational use of Penicil in were significantly lower by the implement of standardized dosing system (P<0.05). Conclusion: The keys of Penicil in’s clinical application are symptomatic treatment, incompatibility, skin test, configuration factors, route of administration and time interval. Strict implementation of standardized medication can improve application of antibacterials.