延边医学
延邊醫學
연변의학
YAN BIAN YI XUE
2014年
16期
44-46
,共3页
手术%发热%氧化应激
手術%髮熱%氧化應激
수술%발열%양화응격
Operation%Fever%Oxidative stress
研究外科术后高热与氧化应激的关联性，为外科术后发热治疗寻找新的思路。方法：研究2012-08？2013-09本院外科34例住院病人，术后检测血清丙二醛浓度变化，比较术后高热组和非高热组病人在术后第2d，4d的MDA浓度差异，同时记录出器官功能障碍的数目，分析MDA浓度与器官功能障碍的关系。结果：术后高热组病人MDA浓度高于非高热组（11.79±1.92)μmol/Lvs(7.21±1.79)μmol/L,P<0.01，MDA浓度与器官功能障碍数目相关。r =0.830，P <0.01)。结论：术后高热患者体内存在严重氧化应激而导致病人器官功能损害。
研究外科術後高熱與氧化應激的關聯性，為外科術後髮熱治療尋找新的思路。方法：研究2012-08？2013-09本院外科34例住院病人，術後檢測血清丙二醛濃度變化，比較術後高熱組和非高熱組病人在術後第2d，4d的MDA濃度差異，同時記錄齣器官功能障礙的數目，分析MDA濃度與器官功能障礙的關繫。結果：術後高熱組病人MDA濃度高于非高熱組（11.79±1.92)μmol/Lvs(7.21±1.79)μmol/L,P<0.01，MDA濃度與器官功能障礙數目相關。r =0.830，P <0.01)。結論：術後高熱患者體內存在嚴重氧化應激而導緻病人器官功能損害。
연구외과술후고열여양화응격적관련성，위외과술후발열치료심조신적사로。방법：연구2012-08？2013-09본원외과34례주원병인，술후검측혈청병이철농도변화，비교술후고열조화비고열조병인재술후제2d，4d적MDA농도차이，동시기록출기관공능장애적수목，분석MDA농도여기관공능장애적관계。결과：술후고열조병인MDA농도고우비고열조（11.79±1.92)μmol/Lvs(7.21±1.79)μmol/L,P<0.01，MDA농도여기관공능장애수목상관。r =0.830，P <0.01)。결론：술후고열환자체내존재엄중양화응격이도치병인기관공능손해。
To investigate the oxidative stress in postoperative fever-patients and explore a new strategy for it. Methods:34 postoperative patients divided into fever- group and non - fever - group were involved. Serum malondialdehyde (MDA); data of were mesured,at the second and :the fourth day after operation. MDA level were compared between,different groups. At the same lime organ function was observed and the numbers of dysfunction organ were recorded. The relationship be-tween MDA level and organ injury vas analyzed. Results:MDA was significantly higher in fever- patients than non- fever- pa? tients ( 11 .79 ± 1.92)μmol/Lvs (7.21 ± 1.79)μmol/L, P<0.01,MDA level was significantly related with thenumbers ofdys-functional organ ( r=0.830, P<0.01). Conclusions:severe oxida-tive stress exists in fever- postoperative patients so that it might result in organ dysfunction.
