CAJ | 학술논문

目的：探讨冷喷法治疗顽固性多发性跖疣的临床效果。方法我院皮肤科门诊于2012年7月至2012年12月收治顽固性多发性跖疣患者43例，采用液氮冷喷法治疗。如患者病患部位角质层较厚，嘱其在治疗前，热水泡脚30分钟，用无菌刀片削去局部的角质层斑块，直到露出向内陷的角化乳头病损面，程度以不出血或有少量点状出血为宜。对周围正常组织加以保护和覆盖，用液氮枪(孔径：0～6mm)喷射液氮于病变部位，至皮损边缘开始变白或疼痛明显，患者难以忍受时停止喷射治疗。病变组织充分冷冻后让其自然解冻为一个冻融周期，连续三个冻融周期为一次治疗。结果43例患者经过1～3次治疗后，其中8例1次治愈(18.6%)，18例2次治愈(41.9%)，12例3次治愈(27.9%)，2例无效(4.7%)，3例复发(4.7%),总有效率为(95.3%)，治愈率（88.4%）。结论冷喷法治疗顽固性多发性跖疣制冷速度快、操作简单、效果显著、病人痛苦较少、复发率低、不留瘢痕，值得推广。
목적：탐토랭분법치료완고성다발성척우적림상효과。방법아원피부과문진우2012년7월지2012년12월수치완고성다발성척우환자43례，채용액담랭분법치료。여환자병환부위각질층교후，촉기재치료전，열수포각30분종，용무균도편삭거국부적각질층반괴，직도로출향내함적각화유두병손면，정도이불출혈혹유소량점상출혈위의。대주위정상조직가이보호화복개，용액담창(공경：0～6mm)분사액담우병변부위，지피손변연개시변백혹동통명현，환자난이인수시정지분사치료。병변조직충분냉동후양기자연해동위일개동융주기，련속삼개동융주기위일차치료。결과43례환자경과1～3차치료후，기중8례1차치유(18.6%)，18례2차치유(41.9%)，12례3차치유(27.9%)，2례무효(4.7%)，3례복발(4.7%),총유효솔위(95.3%)，치유솔（88.4%）。결론랭분법치료완고성다발성척우제랭속도쾌、조작간단、효과현저、병인통고교소、복발솔저、불류반흔，치득추엄。
Objective to explore the clinical effect of cold spray method in the treatment of refractory multiple plantar warts. Methods in our hospital 43 cases outpatient department of dermatology in 2012 July to 2012 december were intractable plantar warts patients, using liquid nitrogen cold spray treatment. if the patients with the disease part with thick cuticle, enjoin its before treatment, 30 minutes hot feet, with a sterile blade cut the stratum corneum plaque, until his inward keratosis nipple lesion surface depression, to no bleeding or small punctate hemorrhage is appropriate. to protect and cover on the surrounding normal tissue, using liquid nitrogen gun (diameter: 0 ~ 6mm) injection of liquid nitrogen on the lesion site, lesion edge began to turn white or obvious pain, stop injection in treatment of the patients with unbearable. lesions after freezing thawing fully let nature take its course for a freeze-thaw cycle, three successive freeze-thaw cycle for one treatment. Results 43 patients after 1 to 3 times after treatment, including 8 cases of cure 1 times (18.6%), 18 cases were cured, 2 (41.9%) of 12 cases of cure 3 times (27.9%), 2 patients (4.7%), 3 cases (4.7%), the total effective rate was (95.3%), the cure rate (88.4%). Conclusion cold spraying method for multiple verruca refrigeration speed, simple operation, obvious effect, less pain, low recurrence rate, no scar treating intractable, worthy of promotion.