CAJ | 학술논문

目的分析与探讨雌孕激素联合治疗青春期功血的临床疗效，为青春期功血的治疗提供科学根据。方法选取本院2011年2月~2013年2月收治的青春期功血患者共60例，采用随机数字表法将其分为两组，观察组30例，对照组30例。两组患者的一般资料差异性无统计学意义具有可比性(>0.05)。观察组给予雌孕激素联合进行治疗，对照组给予雌激素进行治疗，比较两组患者的临床治疗效果以及不良反应。结果观察组患者的有效率为90.0%，对照组患者的有效率为70.0%，两组差异性有统计学意义(<0.05)。观察组患者与对照组患者在治疗过程中均未发生严重不良反应，观察组的完全止血时间为(2.5±1.0)h，控制出血时间为(26.0±10.0)h，对照组控制出血时间为(39.0±12.0)h，完全止血时间为(4.0±1.0)h。观察组患者的上述指标明显短于对照组，差异性有统计学意义(<0.05)。观察组患者的生活质量明显由于对照组患者，差异性有统计学意义(<0.05)。结论采用雌孕激素联合疗法对青春期功血患者具有良好的临床疗效，能够有效达到止血的目的，且不良反应少，因此值得在临床上进行推广与应用，以改善青春期功血患者的生活质量，使其能够更快、更好的康复。
목적분석여탐토자잉격소연합치료청춘기공혈적림상료효，위청춘기공혈적치료제공과학근거。방법선취본원2011년2월~2013년2월수치적청춘기공혈환자공60례，채용수궤수자표법장기분위량조，관찰조30례，대조조30례。량조환자적일반자료차이성무통계학의의구유가비성(>0.05)。관찰조급여자잉격소연합진행치료，대조조급여자격소진행치료，비교량조환자적림상치료효과이급불량반응。결과관찰조환자적유효솔위90.0%，대조조환자적유효솔위70.0%，량조차이성유통계학의의(<0.05)。관찰조환자여대조조환자재치료과정중균미발생엄중불량반응，관찰조적완전지혈시간위(2.5±1.0)h，공제출혈시간위(26.0±10.0)h，대조조공제출혈시간위(39.0±12.0)h，완전지혈시간위(4.0±1.0)h。관찰조환자적상술지표명현단우대조조，차이성유통계학의의(<0.05)。관찰조환자적생활질량명현유우대조조환자，차이성유통계학의의(<0.05)。결론채용자잉격소연합요법대청춘기공혈환자구유량호적림상료효，능구유효체도지혈적목적，차불량반응소，인차치득재림상상진행추엄여응용，이개선청춘기공혈환자적생활질량，사기능구경쾌、경호적강복。
Objective To analysis and discussion of the clinical ef icacy of combination therapy of estrogen and progesterone adolescent dysfunctional uterine bleeding and provide scientific basis for the treatment of adolescent dysfunctional uterine bleeding.Methods The hospital in 2011 February-2013 year in February frompatients with a total of 60 cases of adolescent functional bleeding, were randomly divided into 2 groups, the observation group of 30 cases, 30 cases in the control group. General data, the dif erences between the two groups werenot statistical y significant, comparable ( >0.05). The observation group were given estrogen and progesterone treatment,the control group was given estrogen treatment, compared two groups of patients with clinical curative ef ect and adverse reaction. Results The patients in the observation group was found in 90% of the patients in the control group, the ef ective rate was 70%,there was significant dif erence between two groups ( <0.05). The patients in observation group and control group patients were no serious adverse reactions, the observation group complete hemostasis time is (2.5 ±1) h,to control the bleeding time was (26 ±10) h, the control group to control the bleeding time (39 ±12) h, complete hemostasis time was (4 ± 1) H. The index group were significantly shorter than the control group, the dif erence was statistical y significant ( <0.05). The observation group patients quality of life than the control group, the dif erence was statistical y significant ( <0.05). Conclusion The use of estrogen and progestin therapy has good curative ef ect on adolescent dub patients,can ef ectively achieve the purpose of hemostasis, and less adverse reaction, it is worth popularization and application in clinic.In order to improve the quality of life of the patients with functional uterine bleeding, so that it can be faster, bet er rehabilitation.