中外医学研究
中外醫學研究
중외의학연구
CHINESE AND FOREIGN MEDICAL RESEARCH
2014年
19期
48-49
,共2页
屈朝法%宁彬%董西学%高丽%王洪旗%孙振康
屈朝法%寧彬%董西學%高麗%王洪旂%孫振康
굴조법%저빈%동서학%고려%왕홍기%손진강
肺栓塞%肌钙蛋白I%评价
肺栓塞%肌鈣蛋白I%評價
폐전새%기개단백I%평개
Pulmonary embolism%Cardiac troponin I%Evaluation
目的：探讨肌钙蛋白I(cardial troponin T，cTnI)评价急性高危肺栓塞(acutepulmonary embolism，APE)患者病情严重程度及其预测预后的价值。方法：选取2010年1月-2014年1月在阜阳市人民医院住院的确诊为高危APE患者90例，收集其cTnI检测结果、心脏多普勒指标和临床转归情况；根据临床转归，分为预后良好组和预后不良组，比较两组cTnI的差异，评价cTnI对APE高危患者的病情和预后的预测价值。结果：高危APE患者cTnI指标显著升高，经给予溶栓、抗凝等治疗5 d后随患者的病情好转，cTnI水平明显下降，治疗前后比较差异有统计学意义(P<0.01)。预后不良组治疗后cTnI水平明显高于预后良好组(P<0.01)。结论：cTnI水平能很好评估高危APE患者疾病严重性，治疗后cTnI水平具有预测高危APE患者发生临床不良事件的意义，为临床治疗和预后评估提供客观依据。
目的：探討肌鈣蛋白I(cardial troponin T，cTnI)評價急性高危肺栓塞(acutepulmonary embolism，APE)患者病情嚴重程度及其預測預後的價值。方法：選取2010年1月-2014年1月在阜暘市人民醫院住院的確診為高危APE患者90例，收集其cTnI檢測結果、心髒多普勒指標和臨床轉歸情況；根據臨床轉歸，分為預後良好組和預後不良組，比較兩組cTnI的差異，評價cTnI對APE高危患者的病情和預後的預測價值。結果：高危APE患者cTnI指標顯著升高，經給予溶栓、抗凝等治療5 d後隨患者的病情好轉，cTnI水平明顯下降，治療前後比較差異有統計學意義(P<0.01)。預後不良組治療後cTnI水平明顯高于預後良好組(P<0.01)。結論：cTnI水平能很好評估高危APE患者疾病嚴重性，治療後cTnI水平具有預測高危APE患者髮生臨床不良事件的意義，為臨床治療和預後評估提供客觀依據。
목적：탐토기개단백I(cardial troponin T，cTnI)평개급성고위폐전새(acutepulmonary embolism，APE)환자병정엄중정도급기예측예후적개치。방법：선취2010년1월-2014년1월재부양시인민의원주원적학진위고위APE환자90례，수집기cTnI검측결과、심장다보륵지표화림상전귀정황；근거림상전귀，분위예후량호조화예후불량조，비교량조cTnI적차이，평개cTnI대APE고위환자적병정화예후적예측개치。결과：고위APE환자cTnI지표현저승고，경급여용전、항응등치료5 d후수환자적병정호전，cTnI수평명현하강，치료전후비교차이유통계학의의(P<0.01)。예후불량조치료후cTnI수평명현고우예후량호조(P<0.01)。결론：cTnI수평능흔호평고고위APE환자질병엄중성，치료후cTnI수평구유예측고위APE환자발생림상불량사건적의의，위림상치료화예후평고제공객관의거。
Objective:To evaluate the severity of acute pulmonary embolism(APE) patients by cardial troponin I (cTnI) and explore its prognostic value. Method:From January 2010 to January 2014 in Fuyang People’s Hospital,diagnosed high-risk APE patients with 90 cases were enrolled in this study.The cTnI, heart Doppler index and clinical outcomes were collected.According to the clinical outcome,patients of APE were divided into good prognosis group and poor prognosis group,we compared the differences between two groups of cTnI,predictive value of cTnI in high risk APE patients was evaluated.Result:In the patients with high risk APE,cTnI levels were significantly increased.After thrombolysis,anticoagulation with 5 days in the patients,the levels of cTnI were decreased, with a significant difference before and after treatment(P<0.01).In poor prognosis group the levels of cTnI after treatment were significantly higher than that in the good prognosis group(P<0.01).Conclusion:The levels of cTnI can assess severity of patients with high-risk APE.The levels of cTnI after treatment in the patients can predict the risk of adverse events and prognosis,and provide objective basis for clinical treatment and prognostic evaluation.
