CAJ | 학술논문

目的：探讨分析黄葵胶囊联合ACEI降低慢性肾小球肾炎蛋白尿的临床疗效。方法：将慢性肾小球肾炎120例患者随机分为研究组和对照组，每组60例。对照组患者使用单纯ACEI治疗，研究组患者采用黄葵胶囊联合ACEI治疗，比较两组患者的疗效，尤其是使用的药物对降低慢性肾小球肾炎蛋白尿的临床效果。结果：研究组60例患者经过治疗后显效42例，有效15例，总有效率为95.00％；对照组60例患者经过治疗后显效28例，有效16例，总有效率为73.33％。研究组临床疗效明显高于对照组，差异有统计学意义(P<0.05)。治疗后研究组和对照组的尿蛋白数值均有所降低，研究组尿蛋白的降低幅度显著大于对照组，差异有统计学意义(P<0.05)。结论：采用黄葵胶囊联合ACEI降低慢性肾小球肾炎蛋白尿的临床疗效十分显著，无不良反应，值得在临床上推广使用。
목적：탐토분석황규효낭연합ACEI강저만성신소구신염단백뇨적림상료효。방법：장만성신소구신염120례환자수궤분위연구조화대조조，매조60례。대조조환자사용단순ACEI치료，연구조환자채용황규효낭연합ACEI치료，비교량조환자적료효，우기시사용적약물대강저만성신소구신염단백뇨적림상효과。결과：연구조60례환자경과치료후현효42례，유효15례，총유효솔위95.00％；대조조60례환자경과치료후현효28례，유효16례，총유효솔위73.33％。연구조림상료효명현고우대조조，차이유통계학의의(P<0.05)。치료후연구조화대조조적뇨단백수치균유소강저，연구조뇨단백적강저폭도현저대우대조조，차이유통계학의의(P<0.05)。결론：채용황규효낭연합ACEI강저만성신소구신염단백뇨적림상료효십분현저，무불량반응，치득재림상상추엄사용。
Objective:To explore the clinical effect of Huangkui Capsule combined with ACEI on reducing proteinuria of chronic glomerulonephritis. Method:120 cases of chronic glomerulonephritis were randomly divided into study group(n=60) and control group(n=60).The control group was treated with ACEI alone,the study group was treated with Huangkui Capsule combined with ACEI.The effects,especially the clinical effects of reducing proteinuria of two groups were compared.Result:The total efficiency rate of the study group was 95.00%,and the control group was 73.33%.The effect was better in study group than that in control group,the difference was statistically significant(P<0.05).Urine protein was reduced in both groups,but it decreased significantly in study group than that in control group,the difference was statistically significant(P<0.05).Conclusion:The effect of Huangkui Capsule combined with ACEI on reducing proteinuria of chronic glomerulonephritis is significant,without adverse reaction,and is worth promoting in clinical use.