临床合理用药杂志
臨床閤理用藥雜誌
림상합리용약잡지
CHINESE JOURNAL OF CLINICAL RATIONAL DRUG USE
2014年
20期
3-5
,共3页
不稳定型心绞痛%焦虑%乌灵胶囊%尼可地尔%心理干预%随机平行对照研究
不穩定型心絞痛%焦慮%烏靈膠囊%尼可地爾%心理榦預%隨機平行對照研究
불은정형심교통%초필%오령효낭%니가지이%심리간예%수궤평행대조연구
Unstable angina%Anxiety%wuling capsule%Nicorandil%Psychological treatment%Randomized parallel controlled study
目的：观察尼可地尔联合乌灵胶囊治疗不稳定型心绞痛伴焦虑疗效。方法采用随机平行对照方法，将60例不稳定型心绞痛伴焦虑住院患者采用随机分为对照组予治疗组各30例，2组予常规抗凝、抗血小板聚集、他汀类药物治疗。对照组加予尼可地尔，5mg ~10mg/次，3次/ d；治疗组在对照组基础上加予乌灵胶囊，3粒/次，3次/d，并针对焦虑症状给予心理干预措施，连续治疗2周为1疗程。观测2组临床症状、不良反应。结果治疗组治疗心绞痛总有效率为93.3%，明显高于对照组的76.7%，2组比较差异有统计学意义（P ﹤0.05）；治疗组治疗焦虑症状总有效率为96.7%，明显高于对照组的43.3%，2组比较差异有统计学意义（P ﹤0.05）。治疗过程中对照组出现头痛2例，治疗组出现困倦2例，余无不良反应发生，未影响继续观察。结论乌灵胶囊联合尼可地尔并予心理干预措施治疗不稳定型心绞痛伴焦虑疗效满意。值得临床推广应用。
目的：觀察尼可地爾聯閤烏靈膠囊治療不穩定型心絞痛伴焦慮療效。方法採用隨機平行對照方法，將60例不穩定型心絞痛伴焦慮住院患者採用隨機分為對照組予治療組各30例，2組予常規抗凝、抗血小闆聚集、他汀類藥物治療。對照組加予尼可地爾，5mg ~10mg/次，3次/ d；治療組在對照組基礎上加予烏靈膠囊，3粒/次，3次/d，併針對焦慮癥狀給予心理榦預措施，連續治療2週為1療程。觀測2組臨床癥狀、不良反應。結果治療組治療心絞痛總有效率為93.3%，明顯高于對照組的76.7%，2組比較差異有統計學意義（P ﹤0.05）；治療組治療焦慮癥狀總有效率為96.7%，明顯高于對照組的43.3%，2組比較差異有統計學意義（P ﹤0.05）。治療過程中對照組齣現頭痛2例，治療組齣現睏倦2例，餘無不良反應髮生，未影響繼續觀察。結論烏靈膠囊聯閤尼可地爾併予心理榦預措施治療不穩定型心絞痛伴焦慮療效滿意。值得臨床推廣應用。
목적：관찰니가지이연합오령효낭치료불은정형심교통반초필료효。방법채용수궤평행대조방법，장60례불은정형심교통반초필주원환자채용수궤분위대조조여치료조각30례，2조여상규항응、항혈소판취집、타정류약물치료。대조조가여니가지이，5mg ~10mg/차，3차/ d；치료조재대조조기출상가여오령효낭，3립/차，3차/d，병침대초필증상급여심리간예조시，련속치료2주위1료정。관측2조림상증상、불량반응。결과치료조치료심교통총유효솔위93.3%，명현고우대조조적76.7%，2조비교차이유통계학의의（P ﹤0.05）；치료조치료초필증상총유효솔위96.7%，명현고우대조조적43.3%，2조비교차이유통계학의의（P ﹤0.05）。치료과정중대조조출현두통2례，치료조출현곤권2례，여무불량반응발생，미영향계속관찰。결론오령효낭연합니가지이병여심리간예조시치료불은정형심교통반초필료효만의。치득림상추엄응용。
Objective To observe the effect of nicorandil combined wuling capsule in the treatment of unstable angi-na patients with anxiety. Methods By using random parallel controlled method,60 unstable angina patients with anxiety disor-der were randomly divided into control group and treatment group,each of 30 cases. Both group were received conventional treatment include Anticoagulant,antiplatelet aggregation,statin therapy. The control group were treated with Nicorandil 5mg -10 mg/ time,3 times/ day based on the conventional treatment;the treatment group were given wuling capsule,3 tablet / time,3 times/ day and psychological treatment for 2 weeks on the basis of above treatment. To observe the clinical symptoms and side effects after 1 course of 2 weeks. Results The total efficiency of the treatment group was 93. 3% in treatment of angina pecto-ris,which was higher than 76. 7% of the control group,the difference was statistically significant(P ﹤ 0. 05). The total effi-ciency of the treatment group was 96. 7% in treatment of anxiety symptom,which was higher than 43. 3% of the control group, the difference was statistically significant(P ﹤ 0. 05). In the course of treatment,the control group had headaches in 2 cases, the treatment group appeared sleepiness in 2 cases. There was no other adverse reaction. Conclusion Nicorandil combined wuling capsule and psychological treatment could significantly improve the prognosis of unstable angina patients with anxiety. It is worthy of clinical application.
