CAJ | 학술논문

目的：应用二维斑点追踪技术（2D STE）定量评价冠心病合并2型糖尿病患者心肌功能的早期改变。方法2013年1月至2014年1月间收集首都医科大学宣武医院心脏科经冠状动脉CTA证实主要分支狭窄（＜50％）的患者60例，其中合并2型糖尿（糖尿病组）及未合并糖尿病患者（非糖尿病组）各30例；另选取30例健康人作对照组，测量左室各节段的纵向、圆周及径向的收缩期峰值应变（ε）。结果三组间左室射血分数（ EF）无差异。糖尿病组的纵向基底段、中间段及心尖段纵向收缩期峰值应变显著降低，各个阶段差异均有统计学意义（均P＜0.05）。圆周及径向运动速度指标三组间无明显差异。结论2D STE技术可以发现冠心病合并2型糖尿病患者在左室整体收缩功能出现降低之前，已存在的左室纵向心肌运动功能受损。
목적：응용이유반점추종기술（2D STE）정량평개관심병합병2형당뇨병환자심기공능적조기개변。방법2013년1월지2014년1월간수집수도의과대학선무의원심장과경관상동맥CTA증실주요분지협착（＜50％）적환자60례，기중합병2형당뇨（당뇨병조）급미합병당뇨병환자（비당뇨병조）각30례；령선취30례건강인작대조조，측량좌실각절단적종향、원주급경향적수축기봉치응변（ε）。결과삼조간좌실사혈분수（ EF）무차이。당뇨병조적종향기저단、중간단급심첨단종향수축기봉치응변현저강저，각개계단차이균유통계학의의（균P＜0.05）。원주급경향운동속도지표삼조간무명현차이。결론2D STE기술가이발현관심병합병2형당뇨병환자재좌실정체수축공능출현강저지전，이존재적좌실종향심기운동공능수손。
Objective To evaluate the left ventricular ( LV ) myocardial function in coronary atherosclerosis patients with type 2 diabetes mellitus ( DM ) by two-dimensional speckle tracking echocardiography (2D STE).Methods A total of 60 patients with a diagnosis of coronary atherosclerosis (<50%) were divided into DM and non-DM groups ( n=30 each).And another 30 cases were selected as normal control group.LV regional longitudinal , circumferential and radial peak systolic strain (ε) were measured respectively.Results EF showed no difference among 3 groups.However the peak systolic longitudinal strain (ε) in LV basal segments , middle segments and apical segments were significantly lower in DM group than those in non-DM and control groups ( P<0.05 ).The peak systolic circumferential and radial strain parameters showed no significant difference among 3 groups.Conclusion The systolic longitudinal myocardial function of LV become compromised before reduced LV global systolic function in coronary atherosclerosis patients with type 2 diabetes mellitus.