中国医师杂志
中國醫師雜誌
중국의사잡지
JOURNAL OF CHINESE PHYSICIAN
2014年
z1期
27-29
,共3页
冠心病%内脏脂肪肥胖%氧化应激%胰岛素抵抗%代谢综合征
冠心病%內髒脂肪肥胖%氧化應激%胰島素牴抗%代謝綜閤徵
관심병%내장지방비반%양화응격%이도소저항%대사종합정
Coronary heart disease%Visceral fat%Xidative stress%Insulin resistance%Metabolic syndrome
目的：探讨内脏脂肪肥胖在成年男性冠心病发病中的作用。方法采用64排螺旋CT对入选50名研究对象行冠状动脉CTA检查，将研究对象分为冠心病组及对照组两组，评估各组人群的内脏脂肪面积及代谢指标。并对这些指标与冠心病发病的关系进行相关性分析。结果冠心病组腰围、腰臀比、甘油三酯、胆固醇显著高于对照组。冠心病组空腹胰岛素水平、HOMA-IR及内脏脂肪面积显著高于对照组。空腹胰岛素水平与内脏脂肪面积呈正相关（ r ＝0.779， P ＜0.01）。结论胰岛素抵抗是冠心病患者的核心特征，冠心病患者内脏脂肪面积与空腹胰岛素水平呈正相关，提示内脏脂肪参与了其胰岛素抵抗的发生发展。
目的：探討內髒脂肪肥胖在成年男性冠心病髮病中的作用。方法採用64排螺鏇CT對入選50名研究對象行冠狀動脈CTA檢查，將研究對象分為冠心病組及對照組兩組，評估各組人群的內髒脂肪麵積及代謝指標。併對這些指標與冠心病髮病的關繫進行相關性分析。結果冠心病組腰圍、腰臀比、甘油三酯、膽固醇顯著高于對照組。冠心病組空腹胰島素水平、HOMA-IR及內髒脂肪麵積顯著高于對照組。空腹胰島素水平與內髒脂肪麵積呈正相關（ r ＝0.779， P ＜0.01）。結論胰島素牴抗是冠心病患者的覈心特徵，冠心病患者內髒脂肪麵積與空腹胰島素水平呈正相關，提示內髒脂肪參與瞭其胰島素牴抗的髮生髮展。
목적：탐토내장지방비반재성년남성관심병발병중적작용。방법채용64배라선CT대입선50명연구대상행관상동맥CTA검사，장연구대상분위관심병조급대조조량조，평고각조인군적내장지방면적급대사지표。병대저사지표여관심병발병적관계진행상관성분석。결과관심병조요위、요둔비、감유삼지、담고순현저고우대조조。관심병조공복이도소수평、HOMA-IR급내장지방면적현저고우대조조。공복이도소수평여내장지방면적정정상관（ r ＝0.779， P ＜0.01）。결론이도소저항시관심병환자적핵심특정，관심병환자내장지방면적여공복이도소수평정정상관，제시내장지방삼여료기이도소저항적발생발전。
Objective To examine visceral fat in pathogenesis of coronary heart disease in male adults .Me thods 64-slice spiral CT were measured to separate 50 patient into the following 2 groups:CAD( n =26)and healthy control( n =24).Results Fasting insulin concentration, Insulin resistance index, cholesterol, triglyceride, waist circumference and visceral fat were higher in coronary heart disease group while the lower in healthy control group ( P <0.01 ) .The levels of fasting insulin concentration was posi-tively correlated with visceral fat ( r =0.779 , P <0.01 ) .Conclusions Coronary heart disease is characterized with insulin resist-ance.Fasting insulin concentration and visceral fat are higher in coronary heart disease group than the healthy group , and they may be involved in the pathogenesis of insulin resistance .
