CAJ | 학술논문

目的：探讨血浆D-二聚体（ DD）和纤维蛋白原（ Fib）水平在宫颈癌中的变化情况及其检测的临床意义。方法对经本院病理证实的宫颈癌患者62例，子宫良性肿瘤患者34例及CIN患者42例进行术前血浆DD和Fib水平检测，并与正常对照组（22例）进行比较。结果宫颈癌患者组的DD及Fib水平显著高于对照组；血浆DD及Fib水平随宫颈癌病变的恶性程度升高而呈上升趋势；DD及Fib增高的宫颈癌患者更易发生淋巴结及远处转移。结论随着肿瘤恶性程度的增加，微血栓或血栓危险性增加，在临床上可作为预测癌症患者临床分期及有无转移的辅助性指标。
목적：탐토혈장D-이취체（ DD）화섬유단백원（ Fib）수평재궁경암중적변화정황급기검측적림상의의。방법대경본원병리증실적궁경암환자62례，자궁량성종류환자34례급CIN환자42례진행술전혈장DD화Fib수평검측，병여정상대조조（22례）진행비교。결과궁경암환자조적DD급Fib수평현저고우대조조；혈장DD급Fib수평수궁경암병변적악성정도승고이정상승추세；DD급Fib증고적궁경암환자경역발생림파결급원처전이。결론수착종류악성정도적증가，미혈전혹혈전위험성증가，재림상상가작위예측암증환자림상분기급유무전이적보조성지표。
Objective To explore the clinical significance of plasma D-dimer and fibrinogen level in cervical carcinoma . Methods Sxity-two patients with cervical cancer pathologically proved ,34 cases of benign uterine tumors and 42 cases of CIN were detected plasma DD and Fib levels preoperative , compared with normal control group .Results DD and Fib levels in patients with cervical cancer group were significantly higher than those of control group;With the lesions of cervical cancer malignant degree of plas-ma DD and Fib levels increased;DD and Fib increased cervical cancer occur more frequently in patients with lymph node and distant metastasis .Conclusions Along with the increase of the malignant degree of tumor ,Micro thrombosis or thromboembolism risk increa-ses,In clinical,they can be used as auxiliary index to predict clinical cancer staging and transfer .