实用医学影像杂志
實用醫學影像雜誌
실용의학영상잡지
JOURNAL OF PRACTICAL MEDICAL IMAGING
2014年
4期
229-232
,共4页
体层摄影术,螺旋计算机%诊断显像%肾功能衰竭,慢性
體層攝影術,螺鏇計算機%診斷顯像%腎功能衰竭,慢性
체층섭영술,라선계산궤%진단현상%신공능쇠갈,만성
Tomography,spiral computed%Diagnostic imaging%Kidney failure,chronic
目的：探讨肾脏320排容积CT低剂量灌注成像在肾功能评估中的价值。方法10名双肾功能正常者按照CT扫描剂量分为低剂量组与常规剂量组；13例慢性肾脏病患者（均采用低剂量扫描）根据肾小球滤过率（GFR）分为肾小球功能轻度受损组和中重度受损组；利用320排容积CT灌注成像测定肾皮质血流量并比较各组肾皮质血流量差别。结果320排容积CT灌注扫描均成功。在肾功能正常组中，低剂量组与常规剂量组剂量长度乘积（DLP）分别为417．8 mGy·cm及833．6 mGy·cm，低剂量组射线剂量较常规剂量低约50％；常规剂量组及低剂量组肾皮质肾血流量（BF）分别为424±33 ml·100 g-1·min-1及416±30 ml·100 g-1·min-1，采用t检验，2组间肾皮质BF差异无统计学意义（t＝1．987，P＞0．05）。病例组中，肾功能轻度受损组与中重度受损组肾皮质BF分别为334±40 ml·100 g-1·min-1及236±44 ml·100 g-1·min-1，采用LSD检验两两比较，各病例组与对照组、2个病例组间肾皮质BF差异均有统计学意义（P＜0．05）。结论肾脏320排容积CT低剂量成像能降低辐射剂量，并对慢性肾脏病肾功能进行定量评估。
目的：探討腎髒320排容積CT低劑量灌註成像在腎功能評估中的價值。方法10名雙腎功能正常者按照CT掃描劑量分為低劑量組與常規劑量組；13例慢性腎髒病患者（均採用低劑量掃描）根據腎小毬濾過率（GFR）分為腎小毬功能輕度受損組和中重度受損組；利用320排容積CT灌註成像測定腎皮質血流量併比較各組腎皮質血流量差彆。結果320排容積CT灌註掃描均成功。在腎功能正常組中，低劑量組與常規劑量組劑量長度乘積（DLP）分彆為417．8 mGy·cm及833．6 mGy·cm，低劑量組射線劑量較常規劑量低約50％；常規劑量組及低劑量組腎皮質腎血流量（BF）分彆為424±33 ml·100 g-1·min-1及416±30 ml·100 g-1·min-1，採用t檢驗，2組間腎皮質BF差異無統計學意義（t＝1．987，P＞0．05）。病例組中，腎功能輕度受損組與中重度受損組腎皮質BF分彆為334±40 ml·100 g-1·min-1及236±44 ml·100 g-1·min-1，採用LSD檢驗兩兩比較，各病例組與對照組、2箇病例組間腎皮質BF差異均有統計學意義（P＜0．05）。結論腎髒320排容積CT低劑量成像能降低輻射劑量，併對慢性腎髒病腎功能進行定量評估。
목적：탐토신장320배용적CT저제량관주성상재신공능평고중적개치。방법10명쌍신공능정상자안조CT소묘제량분위저제량조여상규제량조；13례만성신장병환자（균채용저제량소묘）근거신소구려과솔（GFR）분위신소구공능경도수손조화중중도수손조；이용320배용적CT관주성상측정신피질혈류량병비교각조신피질혈류량차별。결과320배용적CT관주소묘균성공。재신공능정상조중，저제량조여상규제량조제량장도승적（DLP）분별위417．8 mGy·cm급833．6 mGy·cm，저제량조사선제량교상규제량저약50％；상규제량조급저제량조신피질신혈류량（BF）분별위424±33 ml·100 g-1·min-1급416±30 ml·100 g-1·min-1，채용t검험，2조간신피질BF차이무통계학의의（t＝1．987，P＞0．05）。병례조중，신공능경도수손조여중중도수손조신피질BF분별위334±40 ml·100 g-1·min-1급236±44 ml·100 g-1·min-1，채용LSD검험량량비교，각병례조여대조조、2개병례조간신피질BF차이균유통계학의의（P＜0．05）。결론신장320배용적CT저제량성상능강저복사제량，병대만성신장병신공능진행정량평고。
Objective To explore the application value of low dose 320-slice volume CT perfusion imaging in the functional assessment of chronic kidney disease. Methods Ten cases of normal renal function were divided into low dose group and routine dose group according to radiation dose. Thirteen cases of chronic kidney disease were di-vided into mild impaired group and severe impaired group according to GFR (glomerular filtrationrate). Applicating 320-slice volume CT perfusion imaging to detect blood flow (BF) of renal cortex. Statistical method was used to com-pare the difference of BF in all groups. Results All of the 320-slice volume CT perfusion scans were successful. DLP (dose length product) of low dose group and routine dose group was 417.8 mGy·cm and 833.6 mGy·cm respectively. Radiation dose of low dose group was reduced about 50%than conventional dose group. BF of routine dose group and low dose group was (424±33) ml·100 g-1·min-1 and (416±30) ml·100 g-1·min-1 respectively, there was no statistical differ-ence in these two groups. BF of mild renal impaired group and severe impaired group was (334±40) ml·100 g-1·min-1 and (236±44) ml·100 g-1·min-1 respectively. BF between case and control group or two case groups had a statis-tically significant difference. Conclusion Low dose 320-slice volume CT perfusion imaging can reduce the radiation dose and evaluate the renal function of chronic kidney disease quantitatively.
